Lazio coach Marco Baroni is expected to pick Loum Tchaouna, Valentin Castellanos and Mattia Zaccagni for his side’s front three to halt Atalanta’s intimidating 11-game winning streak in Serie A.
It kicks off at 20:45 CET (19:45 GMT) at the Stadio Olimpico in Rome.
The two outfits meet each other in a top-of-the-table clash that could either further boost La Dea’s ambitions of winning the title or allow their chasers to catch up.
For such an occasion, Baroni should stick to the 4-3-3 system he recently switched to, with Fisayo Dele-Bashiru set to complete his side’s midfield trio alongside Mateo Guendouzi and Nicolò Rovella.
Centre-backs Mario Gila and Alessio Romagnoli will pair up in the Biancocelesti’s defence, tasked with containing in-form Charles De Ketelaere and Ademola Lookman, who will start up front for the visitors after the news of Mateo Retegui’s injury.
Premier League target Ederson will play in midfield alongside Marten De Roon, while Davide Zappacosta is likely to replace Matteo Ruggeri as a left wing-back after the latter was not called up due to a slight foot injury.
Lazio vs Atalanta – Where to watch on TV
The Stadio Olimpico fixture will be available to watch in the UK via One Football. Fans in the USA can stream it live on Paramount+. If you are in Italy, you can watch the game live both on DAZN and Sky Sport. Football Italia will follow Saturday’s Serie A games live, including Lazio-Atalanta, with a live blog.
Lazio vs Atalanta – Probable line-ups
Lazio (4-3-3): Provedel; Marusic, Gila, Romagnoli, Tavares; Guendouzi, Rovella, Dele-Bashiru; Tchaouna, Castellanos, Zaccagni.
Atalanta (3-4-1-2): Carnesecchi; Kossounou, Hien, Kolasinac; Bellanova, De Roon, Ederson, Zappacosta; Pasalic; De Ketelaere, Lookman.