Groups |
| Liver |
|
AdoMet | AdoHcy | Total GSH | |
(nmol/g) | (nmol/g) | (μmol/g) | |
Experiment 1 |
|
|
|
Control (1 h) (n = 5) | 68.4 ± 7.6 | 28.7 ± 4.7 | 3.29 ± 0.09 |
NECA0.1 (1 h) (n = 5) | 100 ± 6.5* | 13.6 ± 2.6* | 2.27 ± 0.19** |
Experiment 2 |
|
|
|
Control (3 h) (n = 8) | 49.3 ± 7.3 | 20.8 ± 6.6 | 2.72 ± 0.16 |
NECA0.1 (3 h) (n = 9) | 49.4 ± 3.7 | 12.2 ± 2.9 | 1.88 ± 0.14** |
Experiment 3 |
|
|
|
Control (6 h) (n = 4) | 46.3 ± 13.2 | 28.5 ± 6.7 | 2.79 ± 0.11 |
NECA0.1 (6 h) (n = 5) | 46.7 ± 9.8 | 16.0 ± 8.8 | 2.72 ± 0.27 |
Experiment 4 |
|
|
|
Control (1 h) (n = 5) | 79.0 ± 4.3 | 15.2 ± 3.1 | 3.08 ± 0.15 |
NECA0.3 (1 h) (n = 5) | 115 ± 8.7** | 20.3 ± 3.1 | 2.46 ± 0.09** |
Experiment 5 |
|
|
|
Control (3 h) (n = 4) | 52.8 ± 9.0 | 27.7 ± 8.4 | 2.58 ± 0.27 |
NECA0.3 (3 h) (n = 4) | 55.4 ± 5.7 | 9.4 ± 4.4 | 2.10 ± 0.11 |
Experiment 6 |
|
|
|
Control (6 h) (n = 6) | 71.2 ± 12.7 | 20.7 ± 3.7 | 1.81 ± 0.10 |
NECA0.3 (6 h) (n = 7) | 72.1 ± 8.0 | 7.6 ± 2.0** | 1.13 ± 0.07** |
Experiment 7 |
|
|
|
Control (10 h) (n = 6) | 65.0 ± 6.9 | 23.9 ± 2.8 | 3.29 ± 0.29 |
NECA0.3 (10 h) (n = 7) | 72.9 ± 4.8 | 7.9 ± 3.8** | 2.24 ± 0.13** |