Southend secured a convincing victory at out-of-form Yeovil.
The visitors opened the scoring after 20 minutes when Lee Barnard scored.
Peter Clarke headed in Charlie Mulgrew's free-kick in the 41st minute.
Mark Gower headed home from Simon Francis' cross after 64 minutes for the third. Andy Kirk wasted some good opportunities but the former signing from Northampton is still looking for his first goal at Huish Park.