TITLE:
The Influence of Progesterone Gel Therapy in the Treatment of Fibrocystic Breast Disease
AUTHORS:
Milena Brkic, Svetlana Vujovic, Maja Franic Ivanisevic, Miomira Ivovic, Milina Tancic Gajic, Ljiljana Marina, Marija Barac, Branko Barac, Alekasandar Djogo, Gabrijela Malesevic, Damir Franic
KEYWORDS:
Progesterone, Mastalgia, Mastodynia, Fibrocystic Breast Disease
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.5,
April
28,
2016
ABSTRACT: The effect of progesterone therapy on E2/P ratio changes
during the luteal phase, and its consequences are on mastalgia and cyst, within
a fibrocystic breast disease (FBD). Fifty women with FBD were included.
Information for mastalgia and mastodynia were checked with a questionnaire. All
women had (E2) and (P) concentration checked before and during the therapy on
the 21st and 24th day of a cycle, ultrasound measured size and number of cysts
before and during the therapy. T-test, X2-test, McNemar test,
Wilcoxon test and Friedman test were used for statistics. There was a decrease
E2/P relation during the therapy vs. before the treatment p