Hassanvand, F., Mohammadi, T., Aboubzadeh, N., Tavakoli, A. Hassanzadeh, N. Sanikhani, N.S., Azimi, A.I., Mirzaei, H.R., Khodamoradi, M., Goudarzi, K.A, Pourghadamyari, H. and Zaimy, M.A. (2020) Sildenafil Enhances Cisplatin-Induced Apoptosis in Human Breast Adenocarcinoma Cells. Journal of Cancer Research, 16, 1412-1418. - References

Journals by Subject

Publish with us

Follow SCIRP

	+1 323-425-8868
	customer@scirp.org
	+86 18163351462(WhatsApp)
	1655362766

	Paper Publishing WeChat

Article citationsMore>>

Hassanvand, F., Mohammadi, T., Aboubzadeh, N., Tavakoli, A. Hassanzadeh, N. Sanikhani, N.S., Azimi, A.I., Mirzaei, H.R., Khodamoradi, M., Goudarzi, K.A, Pourghadamyari, H. and Zaimy, M.A. (2020) Sildenafil Enhances Cisplatin-Induced Apoptosis in Human Breast Adenocarcinoma Cells. Journal of Cancer Research, 16, 1412-1418.

has been cited by the following article:

TITLE: Cyclic Nucleotide Structural Differentiation of Compounds Modulating Apoptosis and Drug Resistance

AUTHORS: Wynford Robert Williams

KEYWORDS: Cancer, Chemotherapy, Guanosine Cyclic Monophosphate, Molecular Similarity, Multidrug Resistance

JOURNAL NAME: Journal of Biosciences and Medicines, Vol.9 No.8, August 4, 2021

ABSTRACT: Carcinogenesis is associated with malfunction in the cGMP-mediated regulation of cytosolic Ca2+ and reactive oxygen species. Chemotherapy resistant cancer cells are re-sensitised to apoptosis by the action of a substantial number of natural compounds on cell membrane multidrug resistant proteins. Chemical structures of pro-apoptotic and anti-apoptotic compounds demonstrate relative molecular similarity to cGMP. This study uses a computational chemistry program to investigate molecular similarity within cGMP and chemo-preventative structures. Chemotherapeutic drugs and resistance modulators provide multiple fits to a nucleotide template that differ in their relationship to the cyclised ring of cGMP. The alternative fits of drug and modulator structures may relate to the development and unblocking of apoptosis and drug resistance.

Open Access

Articles

The Effect of Sodium Nitrite on Induction of Apoptosis in Human Gastric Adenocarcinoma Epithelia (AGS) Cells

Yanchao Liu, Qiliang Qin, Agula Bo, Hairong Zhang, Qing Zhang, Wenli Hao, Yueling Hu, Juan Sun

Pharmacology & Pharmacy Vol.6 No.11, November 16, 2015

DOI: 10.4236/pp.2015.611052
Open Access

Articles

Biological Activity of N-Hydroxyethyl-4-aza-2,3-didehydropodophyllotoxin Derivatives upon Colorectal Adenocarcinoma Cells

Christian Vélez, Beatriz Zayas, Ajay Kumar

Open Journal of Medicinal Chemistry Vol.4 No.1, February 28, 2014

DOI: 10.4236/ojmc.2014.41001
Open Access

Articles

N-Methylcantharidinimidum Induces Apoptosis in Human Hepatocellular Carcinoma Cell HepG2

Li Tang, Yi Shen

Journal of Biosciences and Medicines Vol.7 No.5, May 17, 2019

DOI: 10.4236/jbm.2019.75006
Open Access

Articles

Nef-M1, a CXCR4 Peptide Antagonist, Enhances Apoptosis and Inhibits Primary Tumor Growth and Metastasis in Breast Cancer

Harvey Bumpers, Ming-Bo Huang, Venkat Katkoori, Upender Manne, Vincent Bond

Journal of Cancer Therapy Vol.4 No.4, June 6, 2013

DOI: 10.4236/jct.2013.44101
Open Access

Articles

Ursolic Acid Derivatives Induced Apoptosis and Reduces the NF-κB in Human Lung Adenocarcinoma Cells

Elaine Carlos Scherrer, Ydia Mariele Valadares, Caio Cesar Souza Alves, Gabriella Freitas Ferreira, Marcela Pereira Leão, Jessica Aline Soares, Fernando Sa Silva, Alessandra Paula Carli, Oswaldo Cardoso Jr., Fabiana Simão Machado, Sandra Bertelli Ribeiro Castro

Journal of Cancer Therapy Vol.10 No.10, October 23, 2019

DOI: 10.4236/jct.2019.1010073

Follow SCIRP

	+1 323-425-8868
	customer@scirp.org
	+86 18163351462(WhatsApp)
	1655362766

	Paper Publishing WeChat

Journals by Subject

Publish with us

Article citationsMore>>

Home

About SCIRP

Service

Policies