RCPE - Research Center Pharmaceutical Engineering GmbH

𝗥𝗲𝗳𝗹𝗲𝗰𝘁𝗶𝗻𝗴 𝗼𝗻 𝗔𝗔𝗧𝗠 𝟮𝟬𝟮𝟯 𝗮𝗻𝗱 𝗟𝗼𝗼𝗸𝗶𝗻𝗴 𝗔𝗵𝗲𝗮𝗱 𝘁𝗼 𝟮𝟬𝟮𝟱 In 2023, AATM brought together over 80 participants and 22 expert speakers from the FDA, top pharmaceutical companies, and academia. The event sparked valuable discussions and set the stage for shaping the future of pharmaceutical development. In 2025, we are building on the success of 2023. Join us in Washington, DC on April 1-2, where 25 distinguished speakers will lead sessions on the solutions accelerating access to medicines. Expect to hear from leaders like Prof. Johannes Khinast (RCPE / Graz University of Technology), Luca Emili (InsilicoTrials), and Matthew M. Bio, Ph.D. (Snapdragon Chemistry, a Cambrex Company). We will cover critical topics such as: • Drug Substance: APIs & Biologics • Drug Product: From Pills to Injectables • Derisking Supply Chains & Transatlantic Partnerships • Modeling & Simulation: From Molecules to Products With around 120 industry professionals, regulators, and decision-makers in attendance, AATM 2025 will be your opportunity to connect and gain actionable insights for driving the future of pharmaceuticals. Find out more and register here: https://lnkd.in/dWWBMKyg #AATM2025 #PharmaInnovation #PharmaceuticalDevelopment

Glad to see our AUTOMATED ELECTROCHEMICAL FLOW PLATFORM out in Angewandte Chemie: https://shorturl.at/nMQL8. While automated batch and flow reactors are established for high throughput experimentation in the context of thermal chemistry and photochemistry, the development of electrochemical platforms can be problematic because of cell miniaturization challenges in batch and difficulties in designing effective single-pass flow systems. In collaboration with Merck Healthcare, we have designed and implemented a new, slug-based automated electrochemical flow platform. This platform was successfully used in the synthesis of a library of Proteolysis targeting chimeras (PROTACs) analogs (44 examples). Furthermore a Design of Experiments (DoE) optimization for an unsuccessful library target was performed in an automated way by the platform, resulting in a 5-fold increase in reaction yield. Another fruitful collaboration between Merck Healthcare, University of Graz and RCPE - Research Center Pharmaceutical Engineering GmbH. Special thanks to Eduardo Rial Rodríguez, Jason Williams, David Cantillo, Gabriele Laudadio from our team in Graz and Hans-Michael Eggenweiler and his team at Merck Healthcare: #Automation #Electrochemistry #PROTACs #CRBN #flowchemistry #pharmaceuticals

Medikamenten-Engpässe mit KI vermeiden 💊🤖 Fraunhofer Austria leitet das FFG-geförderte Projekt „Remedy", um die Versorgungssicherheit für Medikamente in Österreich zu stärken. Gemeinsam mit RCPE - Research Center Pharmaceutical Engineering GmbH, der Carl von Ossietzky Universität Oldenburg und der WU (Wirtschaftsuniversität Wien) wird geprüft, ob Künstliche Intelligenz genutzt werden kann, um Lieferengpässe frühzeitig zu prognostizieren – ein entscheidender Schritt für die medizinische Versorgungssicherheit. Das interdisziplinäre Team aus Technik- und Rechtsexpert:innen untersucht innerhalb eines Jahres, wie heterogene Daten wie Lagerbestände, Infektionszahlen oder internationale Ereignisse genutzt und harmonisiert werden können. Ziel ist ein Konzept, das rechtliche und technische Rahmenbedingungen berücksichtigt und die Zahl kritischer Arzneimittel-Engpässe reduziert. 👉 Gemeinsam für innovative Lösungen: https://lnkd.in/dnvcM3hy Interessiert? Kontaktieren Sie unseren Fraunhofer Austria Experten Sebastian Kreuter #KünstlicheIntelligenz #Medizin #Innovation #Forschung #FraunhoferAustria FFG Österreichische Forschungsförderungsgesellschaft mbH Fotocredit: Shutterstock/i viewfinder

𝗠𝗲𝗲𝘁 𝗼𝘂𝗿 𝗶𝗻𝘀𝗽𝗶𝗿𝗶𝗻𝗴 𝗺𝗶𝗻𝗱𝘀! This week we introduce Simone Eder, one of the inspiring minds behind our success! “My name is Simone Eder. I have a master’s degree in Chemistry and a PhD in Natural Sciences. I currently work as a Principal Scientist and Group Leader at RCPE in Area III: Next-Generation Manufacturing. I chose a career in science because I enjoy working in an interdisciplinary team, facing new challenges and creating innovative solutions every day, rather than doing routine work. I believe that working in science offers you a great opportunity to constantly learn new things and get in touch with interesting, inspiring people. You stay up to date in your working area, can create new fields of expertise and eventually grow and make a real difference – not only to the scientific community but also to society. Currently, I work in the field of personalized manufacturing, specifically in 3D-printing medical and pharmaceutical inserts and implants, as well as oral tablets. During this work, we developed 3D-printed personalized vaginal inserts to treat stress urinary incontinence, also known as pessaries, which are an easy and straightforward treatment strategy. This work yielded a nomination for the Houska Prize – the greatest private award for application-oriented innovation and research in Austria – showing the relevance of our work to female patients. In the future, I hope we will develop other innovative products that fit the requirements of specific patient groups, such as women, children, and elderly people making their lives easier. Eventually, it would be groundbreaking to develop platform technologies that allow for tailoring the treatment strategy specifically towards the genetic characteristics, lifestyle, and preferences of individual patients.” Stay tuned to discover more of the innovative minds driving our success! #MeetRCPE #PersonalizedMedicine #3DPrinting #WomenInScience

𝗝𝗼𝗶𝗻 𝘂𝘀 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗔𝗔𝗧𝗠 𝗪𝗼𝗿𝗸𝘀𝗵𝗼𝗽 𝗶𝗻 𝗪𝗮𝘀𝗵𝗶𝗻𝗴𝘁𝗼𝗻, 𝗗𝗖! Be part of the Accelerating Access to Medicines workshop on April 1-2, 2025, at the Austrian Embassy. Connect with experts from the FDA, leading pharma companies, and academia to discuss solutions for overcoming development bottlenecks and speeding up access to medicines. Why Attend? • Learn actionable solutions to improve your processes. • Stay ahead with the latest pharmaceutical technologies. • Network with industry leaders, decision-makers, and suppliers. Sign up by December 15 to secure your early bird ticket! https://lnkd.in/dWWBMKyg

This list is out, and this year we have 3 partners on Stanford's "Top 2% Scientists" list. Congrats to Vinković Vrček Ivana (Institute for Medical Research and Occupational Health), Johannes Khinast (RCPE - Research Center Pharmaceutical Engineering GmbH) for making the 2024 list, and Jesus M. de la Fuente (CSIC) for making the "career-long" list, of top cited resesarchers! Be proud of this recognition for your hard work! 🔬 🎉

𝗕𝗼𝗼𝘀𝘁 𝗬𝗼𝘂𝗿 𝗘𝘅𝗽𝗲𝗿𝘁𝗶𝘀𝗲 𝗶𝗻 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝗮𝗹 𝗠𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴! Looking to strengthen your knowledge of pharmaceutical production? RCPE has developed two online courses in collaboration with Technische Universität Graz to provide in-depth insights into continuous manufacturing and material science: 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗳𝗼𝗿 𝗖𝗼𝗻𝘁𝗶𝗻𝘂𝗼𝘂𝘀 𝗣𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲𝘀 • Discover the advantages of continuous manufacturing and its core concepts. • Learn about direct compaction, dry- and wet granulation, and how material and process properties interact. • Understand key control strategies for ensuring quality and efficiency. 𝗠𝗮𝘁𝗲𝗿𝗶𝗮𝗹 𝗦𝗰𝗶𝗲𝗻𝗰𝗲 𝗳𝗼𝗿 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴 • Master the handling of powders and solid dosage forms while tackling common challenges. • Explore techniques to analyze particle characteristics and optimize tablet formulations. • Gain strategies to address segregation and refine powder sampling methods. Join these courses for free or unlock exclusive content and earn a certificate by upgrading. Start your learning journey today: • Technology for Continuous Production of Medicines: https://lnkd.in/dfnqmUps • Material Science for Medicine Processing: https://lnkd.in/dbVfMvZq #EdXCourses #PharmaceuticalManufacturing #MaterialScience #ContinuousManufacturing

𝗝𝗼𝗶𝗻 𝗼𝘂𝗿 𝘁𝗲𝗮𝗺 𝗮𝘀 𝗮 𝗟𝗮𝗯 𝗧𝗲𝗰𝗵𝗻𝗶𝗰𝗶𝗮𝗻! Are you skilled in laboratory techniques and ready to support pharmaceutical product and process development? We are looking for a motivated (Senior) Laboratory Technician to join our Technical Operations team. In this role, you’ll manage technical resources, conduct experiments, and ensure compliance with quality and safety standards. This is a unique opportunity to work with advanced equipment such as extruders, spray dryers, and compression machines in a dynamic research environment.   If you have a background in chemistry or a related field, experience in R&D laboratories, and strong English skills, we’d love to hear from you! Find more about this and other positions here: https://lnkd.in/dUyt_wGz #RCPEisHiring #PharmaCareer #LabTechnician

I am happy to announce that University of Graz and RCPE - Research Center Pharmaceutical Engineering GmbH have signed a licensing agreement with Sigma-Aldrich for the commercial development of our spinning cylinder electrode reactor (SCER) technology.     This reactor concept permits scaling electrochemical transformations from the milligram scale to kilogram quantities without the need for re‑optimization of reaction conditions. The reactor can operate both in batch and continuous mode, can process slurries and handle gas evolution. The technology has been demonstrated for the electrosynthesis of several key API intermediates, including adrenosterone and noroxycodone. 👉First disclosure of the reactor with several applications here: https://lnkd.in/dX_gS-8n 👉Case study with Pfizer: https://lnkd.in/d2w_yHdB 👉Case study with Merck/MSD: https://lnkd.in/dZqUbsW4 👉Case study with Eli Lilly and Company: https://shorturl.at/yLM1E We are looking forward to seeing this technology commercialized and put into the hands of synthetic organic electrochemists!

𝗝𝗼𝗶𝗻 𝗼𝘂𝗿 𝘁𝗲𝗮𝗺 𝗮𝘀 𝗮 𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁 𝗶𝗻 𝘁𝗵𝗲 𝗘𝗨 𝗽𝗿𝗼𝗷𝗲𝗰𝘁 𝗣𝗵𝗮𝗿𝗺𝗘𝗖𝗢! Are you passionate about engineering-driven research in pharmaceutical processes? We’re seeking a Scientist (with the possibility to do a PhD) to optimize biological systems as part of an exciting EU collaboration. In this role, you’ll develop advanced models, control algorithms, and digital twin structures, shaping innovations in biopharma. If you have a Master’s in engineering and experience or interest in MATLAB, Simulink, and Python, we encourage you to apply! Find more about this and other positions here: https://lnkd.in/db6ETjwX #RCPEisHiring #PharmaCareer #EngineeringResearch #Biopharma