MindBio Therapeutics reposted this
MindBio Therapeutics Reports a 72% Reduction in Severity of Depression Sustained Six Months After Treatment in Clinical Trials: https://lnkd.in/e_3fGYrv
MindBio Therapeutics is a clinical stage drug development company that is pioneering psychedelic microdosing in multiple Phase 2B clinical trials. MB22001 is MindBio's lead candidate drug, a proprietary titratable form of Lysergic Acid Diethylamide (LSD) designed for safe take home microdosing. Phase 2 clinical trials are underway. Clinical trials include: 1. Phase 2B trial in patients with Major Depressive Disorder 2. Phase 2B trial in patients with Late Stage Cancer and Depression The Phase 2B trial in patients with Major Depressive Disorder will evaluate the effectiveness of MB22001 in treating depression. We know from an open label Phase 2A trial in 20 patients with Major Depressive Disorder, that 53% of patients with depression were in complete remission from their depression at week 8. This is represented by a 14.1 point drop in MADRS score (Montgomery-Asberg Depression Rating Scale). The 60% overall improvement in depressive symptoms and previous successful trials in healthy individuals gives the company confidence going into Phase 2B trials that MB22001 is a very promising treatment for Depression. The Phase 2 clinical trials for cancer patients will evaluate the feasibility of conducting a randomised controlled trial comparing psychedelic-microdose assisted – Meaning Centred Psychotherapy to standard Meaning-Centred Psychotherapy in people who have advanced cancer and anxiety or depression. Participants will be randomised to receive psychotherapy alongside doses of either an LSD microdose or placebo. The feasibility, acceptability, safety and potential psychological benefits of this intervention will be assessed. Our findings will inform the development of a larger trial and provide initial indication of potential benefits of psychedelic microdosing in advanced cancer.
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MindBio Therapeutics reposted this
MindBio Therapeutics Reports a 72% Reduction in Severity of Depression Sustained Six Months After Treatment in Clinical Trials: https://lnkd.in/e_3fGYrv
MindBio Therapeutics reposted this
🔥 This is an incredible advancement in novel treatments for depression.
MindBio Therapeutics reposted this
MindBio Therapeutics Announces Clinical Trial Milestone In Phase 2B Microdosing Trials Targeting Existential Distress, Depression & Anxiety In Advanced Stage Cancer: https://lnkd.in/e7YCrzYg
MindBio Therapeutics reposted this
Advanced stage cancer patients commonly suffer from end of life distress, depression and anxiety in addition to the burden of their cancer treatment and diagnosis. Anti-depressant medications have limited success in alleviating these symptoms of distress in this vulnerable group of patients. 🔥 So, we are pleased to have dosed the 20th patient in this Phase 2B randomised controlled trial with MB22001 in the hope that it may be effective addition to Meaning Centred Psychotherapy and help successfully alleviate symptoms of depression, anxiety and existential distress in patients with advanced stage cancer.
MindBio Therapeutics reposted this
MindBio Therapeutics Completes Final Post Treatment Milestone in Phase 2A Microdosing Depression Clinical Trial: https://lnkd.in/d_vKbgit
MindBio Therapeutics reposted this
MindBio Therapeutics Develops Long Term Shelf-Stable Microdosing Formulation and is Progressing in Multiple Phase 2B Clinical Trials: https://lnkd.in/eDimy4mt
MindBio Therapeutics reposted this
MindBio Therapeutics Enrolls 25th Participant into Landmark Take-Home Microdosing Depression Trial: https://lnkd.in/eWr72XGp
MindBio Therapeutics reposted this
The current treatments for depression are not working, and there is a need for a significant step change in the way we treat mental health conditions. Excited to discuss new treatments for depression and the progress of our portfolio company MindBio Therapeutic's (CSE: MBIO) in Phase 2B Microdosing Depression clinical trials. We are entering our 25th participant into this randomized, double dummy, triple-blind, active placebo-controlled clinical trial. Join me for this important conversation. #depression #mentalhealth #clinicaltrials
MindBio Therapeutics reposted this
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