Princess Margaret Genomics Centre

🚀 We're Hiring! Join the Princess Margaret Genomics Centre Team 🚀 The Princess Margaret Genomics Centre is expanding, and we're excited to announce several job openings! 🔬 Research Technician II positions: Position 1: https://lnkd.in/egZACUv5 Position 2: https://lnkd.in/ef-ZvH3k 🔬 Research Technician III position: Position 3: https://lnkd.in/e-zvq_HU As a core service provider lab, we contribute to groundbreaking research by many scientists and experts. We are excited to receive resumes from talented individuals ready to join our dynamic team and advance genomics research. Apply now and be part of our mission! #Hiring #Genomics #ResearchJobs #JoinOurTeam #PrincessMargaretGenomicsCentre

Applications are now open to an Introductory Spatial 'Omics Analysis (Visium HD) workshop: https://lnkd.in/emvKkxYb There is no fee of participation in this workshop, which is funded by the Brain Single Cell Initiative (BSCI), an innovative arrangement between the Government of Canada (through Health Canada), Brain Canada Foundation (BCF), and University Health Network (UHN). #Genomics at UHN Research & Innovation Cores

Here’s a sneak peek at the exciting youth tours recently held at University Health Network. We had an amazing time engaging with bright high school minds from across Toronto at our facility at Princess Margaret Genomics Centre! Glad to be a part of their #STEMeducation journey along with the UHN STEM Pathways.

📢 Join Us for a Lunch & Learn! 📢 Scaling Single Cell Across Samples and Modalities Date: Tuesday, November 19 Time: 12:30 - 1:30 PM EST Location: Red Seminar Room at Donnelly Centre, 160 College Street, Toronto, ON M5S 3E1   Session Insights: ➤ Discover Scale Bio's cutting-edge, scalable, and cost-effective single cell solutions. ➤ Learn how single cell analysis can unlock profound biological insights in large-scale studies. ➤ Explore techniques for sample multiplexing and optimization to boost research efficiency. 🍽️ Free Lunch Provided! 🍽️ Don't miss this opportunity to enhance your research capabilities.  Register here: https://lnkd.in/ePBujbut   #LunchAndLearn #SingleCellAnalysis #ResearchInnovation #UHNCores #Genomics #Omics

📣 PMGC is now the member of Service and Technology Endorsed Provider (STEP) Program with Scale Biosciences.  🔬 Advance your Single Cell Research with Scale Biosciences methylation and RNA assays. Reach out to us to learn more about how Scale Bio assays (or kit services) can be used to unearth cellular heterogeneity and underlying mechanisms of Biology and Diseases. Contact us at geneservice@pmgenomics.ca to discuss your #ScaleBio project.

We are excited to offer an early-adopter service discount of 27.5% on Xenium Prime 5k services through the end of 2024. Please reach out to discuss how you can leverage this opportunity for your research: geneservice@pmgenomics.ca

Come, meet us at the Translational applications in single cell and spatial multiomics Symposium, happening tomorrow (September 24, 2024) at 9:30 AM–5:00 PM ET. LOCATION MaRS Discovery District, MaRS Centre - Auditorium 101 College Street, Suite 100, Toronto, ON M5G 1L7 Follow this link for more details: https://lnkd.in/ePivQdgs

Our Introductory Spatial ‘OMICS Analysis Workshop (ISO2024 - #CBW workshop) is up now for everyone to watch and learn. https://lnkd.in/efq9hadq Though, we used the Xenium as our model machine of choice, our workshop is applicable to other single molecular platforms (I.e Merscope, CosMX) and many of the ideas are also applicable to array-based spatial platforms (I.e Stereo-seq, VisiumHD). 🔲 Module 1 - Garbage-in, garbage-out The focus was on bench-work, the challenges in tissue-prep and the due-diligence required. We had experts sharing real world experience into the art of tissue management and preparation, including a guide to panel design. 🔲 Module 2 - Pre-processing steps Where we took a deeper-dive than usual in understanding transcript quality & distribution and how these have an impact on downstream modelling. 🔲 Module 3 - Building your spatial model In spatial analysis, the beauty lies in capturing the spatial patterns of distributions. Using #Banksy as our method of choice, we challenged our participants to think critically and logically the choices they make when deciding on a spatial model. 🔲 Module 4 - Drawing Boundaries The aim was to encourage participants to understand their images and the nature of tissue structure and to introduce the principles behind segmentation. We compared a publicly available deep-learning image based segmentation output, from 10x, with a transcript guided alternative (#Baysor) 🔲 Module 5/6 - Realizing the spatial potential in your dataset.  We wanted to introduce the fundamental concepts behind statistically evaluating the spatial patterns in your dataset. Our eyes can be mis-leading and seemingly non-random patterns can be truly just random constructions. Touching upon this topic briefly to give a taste to our participants to think beyond the end results of their analysis. ---------------------------------------- 1️⃣ This was alot over two days. If we had intentionally made some modules brief and left out some areas, it was to avoid overwhelming our diverse audience. At the same time, we tried to find a sweet spot in our teaching speed. Therefore, feedback is always welcome. Please leave us a note, email, comment if you found the materials useful and on how we can improve. 2️⃣Github : There are some additional scripts that has been included post-workshop and we will continue to improve on this from time to time. 3️⃣We thank our organizers from the Brain Single Cell Initiative(Princess Margaret Genomics Centre) and Bioinformatics.ca (Canadian Bioinformatics Workshops) who provided this opportunity for Panoramics-A Vision to develop the course content for this workshop. 🔆 We are incredibly proud to share that this was an all-women team of instructors and TAs and we are confident this will only encourage more members from all communities to join us to lead the way in training for a better future. 🔆 Nia Hughes Ashleigh Willis Melanie Peralta Farzaneh Aboualizadeh

Attention PMGC Spatial Profiling Customers, we’re pleased to offer a 35% discount on our standard Xenium profiling services for a limited time.

It fun great to host two groups of enthusiastic STEM summer students!