Alexis Technologies

🌟 Exciting news in respiratory research! 🌟 AlveoliX , in collaboration with Vitrocell Systems GmbH Systems, the University of Bern, and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), has published a groundbreaking study in 𝘉𝘪𝘰𝘦𝘯𝘨𝘪𝘯𝘦𝘦𝘳𝘪𝘯𝘨 & 𝘛𝘳𝘢𝘯𝘴𝘭𝘢𝘵𝘪𝘰𝘯𝘢𝘭 𝘔𝘦𝘥𝘪𝘤𝘪𝘯𝘦. 🫁 Our research introduces a stretchable human lung-on-chip model, designed to simulate alveolar inflammation and evaluate anti-inflammatory drug responses. This innovative technology not only mimics the human alveoli's microenvironment but also paves the way for high-fidelity disease modeling and personalized treatment strategies. By reducing reliance on animal testing, we are committed to advancing ethical research practices in medicine. Discover the full details of our collaborative efforts and their impact on the future of lung disease therapies in the complete press release below. Thank You for this great collaboration Claus-Michael Lehr Nicole Schneider-Daum Tobias Krebs Vitrocell Systems GmbH Olivier Guenat ARTORG Center for Biomedical Engineering Research Arunima Sengupta, Ph.D. Alexis Technologies Clémentine Richter Andreas Hugi Janick Stucki Latta Lorenz Daria Harig Felix Stöckle Alberto Hidalgo Brigitta Loretz Franziska Lautenschlaeger sitem-insel AG be-advanced AG Startupticker.ch Innovation Office University of Bern #LungOnChip #RespiratoryResearch #BiomedicalInnovation #Collaboration #AlveoliX

EUROTOX Congress Copenhagen has concluded, and it was a pleasure to connect with our valued partners Vitrocell Systems GmbH and Alexis Technologies who were instrumental in showcasing our joint solution, the new AX Cloud. 🫁The response to our innovative approach to assessing toxicity with our Lung-on-a-Chip was overwhelming, and we look forward to continuing to assist new clients in addressing their future challenges! On top of our advancements in the lung field, we are also very excited to announce that we were able to qualify our 🦠gut model for safety and toxicology testing, with the ability to prime the gut cells with the physiological-relevant peristaltic 〰️ motion of the AXBarrier-on-Chip System. Additionally, this year we launched our 🫘kidney-on-chip project, further expanding our ability to support the toxicology industry. From pollution 🌧️ and pesticide🥬 risk assessment to cosmetics 💄🫧 and food 🍼🥩safety testing our technology enables a wide range of applications. A special thanks to Alexis Technologies Arunima Sengupta, Ph.D. for the contributions in in-vitro inhalation toxicity to our ongoing success! We look forward to seeing you all at next year’s event! #Toxicology #AXCloud #Vitrocell #LungOnAChip #GutOnAChip #KidneyOnAChip #PollutionTesting #PesticideSafety #CosmeticsTesting #Innovation AstraZeneca INL - International Iberian Nanotechnology Laboratory Chiesi Group Fachhochschule Nordwestschweiz FHNW Labcorp Drug Developement..  Cargill LEARN Project UNLOOC Chips JU Project

🌍 𝗩𝗼𝗶𝗰𝗲𝘀 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗹𝘃𝗲𝗼𝗹𝗶𝘅 𝗣𝗮𝗿𝘁𝗻𝗲𝗿 𝗖𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆! 𝗪𝗲 𝗮𝗿𝗲 𝗱𝗲𝗹𝗶𝗴𝗵𝘁𝗲𝗱 𝘁𝗼 𝗰𝗼𝗹𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗲 𝘄𝗶𝘁𝗵 𝗲𝘀𝘁𝗲𝗲𝗺𝗲𝗱 𝗽𝗮𝗿𝘁𝗻𝗲𝗿𝘀 𝗮𝗻𝗱 𝘀𝗽𝗲𝗰𝗶𝗮𝗹𝗶𝘇𝗲𝗱 𝗰𝗹𝗶𝗻𝗶𝗰𝗶𝗮𝗻𝘀 𝗹𝗶𝗸𝗲 Young-Jae Cho! In collaboration with Arunima Sengupta, Ph.D. from Alexis Technologies, we are working on the critical issue of air pollutants and toxic inhaled nanoparticles, such as pesticides and silicones, which pose significant daily risks to human health. Assessing the impact of these pollutants is vital, as they are major contributors to respiratory diseases, cardiovascular issues, and other chronic health conditions. Our partnership is key to developing effective public health policies and securing a healthier future for all. ❝ 𝗜 𝗯𝗲𝗹𝗶𝗲𝘃𝗲 𝗼𝘂𝗿 𝗽𝗮𝗿𝘁𝗻𝗲𝗿𝘀𝗵𝗶𝗽 𝘄𝗶𝗹𝗹 𝗯𝗲 𝗰𝗿𝘂𝗰𝗶𝗮𝗹 𝗮𝗺𝗶𝗱𝘀𝘁 𝘁𝗵𝗲 𝗰𝘂𝗿𝗿𝗲𝗻𝘁 𝗰𝗹𝗶𝗺𝗮𝘁𝗲 𝗰𝗿𝗶𝘀𝗶𝘀 𝗮𝗻𝗱 𝗳𝘂𝘁𝘂𝗿𝗲 𝗿𝗲𝘀𝗽𝗶𝗿𝗮𝘁𝗼𝗿𝘆 𝗰𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲𝘀. ❞ Thank you, Young-Jae Cho, for your dedication and collaboration! #Collaboration #EnvironmentalHealth #Sustainability #PublicHealth #OrganOnChip #LungOnChip Seoul National University

>> Intensive experience exchange at VITROCELL User Group Meeting 2024 in Nice / France We had an excellent meeting with our customers – one day before the LIVe Lung Conference organized by ALTERTOX and Epithelix. The event offered a mix of insights on VITROCELL‘s product/application strategy and customer experiences with the products. We thank all participants for the lively discussions and positive feedback on our performance! The proposal to intensify an application-oriented dialogue by smaller workshops was taken up: we plan to start with a first workshop on VITROCELL Cloud applications at the Luxembourg Institute of Science and Technology (LIST) in the second half of 2024. #LIVe2024 #invitro

🔍 𝑻𝒉𝒊𝒏𝒌𝒊𝒏𝒈 𝒐𝒖𝒕𝒔𝒊𝒅𝒆 𝒕𝒉𝒆 𝑩𝒐𝒙—this year’s theme at the #LIVe2024 event in #Nice encapsulates the innovative spirit driving the future of lung in vitro models. 𝘋𝘢𝘺 1 has been a whirlwind of insights and groundbreaking discussions, some prominent highlights: 𝐊𝐢𝐜𝐤𝐨𝐟𝐟: Samuel Constant and Francois Busquet , PhD from ALTERTOX set the stage with an engaging icebreaker, leading into a deep dive on the increasing global market trends for lung in vitro models. A compelling start! 𝐁𝐫𝐞𝐚𝐤𝐢𝐧𝐠 𝐁𝐚𝐫𝐫𝐢𝐞𝐫𝐬: Claus-Michael Lehr delivered a fascinating talk on drug delivery across barriers, also showcasing the capabilities of AlveoliX 's breathing lung on chip for anti-infective therapy studies. 𝐏𝐚𝐭𝐢𝐞𝐧𝐭-𝐂𝐞𝐧𝐭𝐫𝐢𝐜 𝐈𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐨𝐧𝐬: Giulia Raggi presented a cutting-edge patient-derived lung on-chip model designed to study vascular leak syndrome, pushing the boundaries of the AlveoliX AX barrier on-chip 𝐑𝐞𝐭𝐡𝐢𝐧𝐤𝐢𝐧𝐠 𝐏𝐫𝐞𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐀𝐬𝐬𝐚𝐲𝐬: Josue Sznitman challenged us to "think different" about advancing preclinical inhalation assays with bioengineered lung models—a thought-provoking session that broadened our perspectives. 𝐀 𝐇𝐨𝐥𝐢𝐬𝐭𝐢𝐜 𝐀𝐩𝐩𝐫𝐨𝐚𝐜𝐡: Nuria Roldan from PETA Science Consortium International e.V. advocated for a multi-pronged approach to enhance in vitro inhalation toxicity testing, aligning with our commitment to ethical and effective scientific methods. Vitrocell Systems GmbH AlveoliX Alexis Technologies #LIVe2024 #inVitroModels #LungOnChip #InhalationToxicity #PreclinicalInnovation #AlexisTechnologies

🔍 𝑻𝒉𝒊𝒏𝒌𝒊𝒏𝒈 𝒐𝒖𝒕𝒔𝒊𝒅𝒆 𝒕𝒉𝒆 𝑩𝒐𝒙—this year’s theme at the #LIVe2024 event in #Nice encapsulates the innovative spirit driving the future of lung in vitro models. 𝘋𝘢𝘺 1 has been a whirlwind of insights and groundbreaking discussions, some prominent highlights: 𝐊𝐢𝐜𝐤𝐨𝐟𝐟: Samuel Constant and Francois Busquet , PhD from ALTERTOX set the stage with an engaging icebreaker, leading into a deep dive on the increasing global market trends for lung in vitro models. A compelling start! 𝐁𝐫𝐞𝐚𝐤𝐢𝐧𝐠 𝐁𝐚𝐫𝐫𝐢𝐞𝐫𝐬: Claus-Michael Lehr delivered a fascinating talk on drug delivery across barriers, also showcasing the capabilities of AlveoliX 's breathing lung on chip for anti-infective therapy studies. 𝐏𝐚𝐭𝐢𝐞𝐧𝐭-𝐂𝐞𝐧𝐭𝐫𝐢𝐜 𝐈𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐨𝐧𝐬: Giulia Raggi presented a cutting-edge patient-derived lung on-chip model designed to study vascular leak syndrome, pushing the boundaries of the AlveoliX AX barrier on-chip 𝐑𝐞𝐭𝐡𝐢𝐧𝐤𝐢𝐧𝐠 𝐏𝐫𝐞𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐀𝐬𝐬𝐚𝐲𝐬: Josue Sznitman challenged us to "think different" about advancing preclinical inhalation assays with bioengineered lung models—a thought-provoking session that broadened our perspectives. 𝐀 𝐇𝐨𝐥𝐢𝐬𝐭𝐢𝐜 𝐀𝐩𝐩𝐫𝐨𝐚𝐜𝐡: Nuria Roldan from PETA Science Consortium International e.V. advocated for a multi-pronged approach to enhance in vitro inhalation toxicity testing, aligning with our commitment to ethical and effective scientific methods. Vitrocell Systems GmbH AlveoliX Alexis Technologies #LIVe2024 #inVitroModels #LungOnChip #InhalationToxicity #PreclinicalInnovation #AlexisTechnologies

🌙 Sleepless in Seattle? Yes, because there is SO MUCH exciting stuff ongoing at the MPS World Summit next week! 🌟Booth #67 is the place to be ;-)    We're happy to share that our team members, Lea Lara de Maddalena and Giulia Raggi , will be presenting their groundbreaking research!    Talk: 🎤 Giulia will be discussing "Patient-derived lung-on-chip for safety assessment of cancer immunotherapy" on Wednesday, June 12th from 12:40-13:00 in Track 3, Session 3.3.    Posters:   📌 Lea, Poster Board #16: "A novel alveolus-on-chip model of SARS-CoV-2 infection for pre-clinical application" on Tuesday, June 11th from 10:00-11:30 in Track 1.   📌 Giulia, Poster Board #111: "A novel human 3D peristaltic simulating Gut-on-Chip platform for predictive testing of new barrier-protecting drug candidates" on Tuesday, June 11th from 16:30-18:00 in Track 1.   📌 Lea, Poster Board #308: "AXILD model: Efficacy testing for new clinical drug candidates to treat pulmonary fibrosis" on Thursday, June 13th from 10:00-11:30 in Track 4.    Lea and Giulia are happy to talk and check synergies—let's connect and explore new possibilities together! 🤝AlveoliX booth: #67    For more details, check out the event here: https://lnkd.in/ezwpKeu8   #MPSWorldSummit #LungOnChip #GutOnChip #SARSCoV2Research #CancerImmunotherapy #DrugDevelopment #PulmonaryFibrosis #Innovation #Collaboration