PHRT - Personalized Health and Related Technologies

Save the Date! We are very pleased to announce the upcoming symposium “From Technology to Treatment: Advancing Precision Medicine”, to be held on 28–29 August 2025 at the Main Building of ETH Zürich, hosted by PHRT - Personalized Health and Related Technologies and Swiss Personalized Health Network (SPHN). This two-day event will bring together leading experts from academia, healthcare, and industry to explore the latest breakthroughs in personalized medicine. We’ll focus on how cutting-edge technologies are transforming clinical practice and improving patient care.  Key highlights include:  • Keynote lectures on advances in personalized medicine in Switzerland and globally • A panel discussion with thought leaders addressing the future of personalized medicine • Presentations on groundbreaking projects that translate research into real-world clinical applications • Opportunities for national and international collaborations to accelerate progress in the field Save the date and join us for what promises to be an inspiring and forward-thinking symposium! More details on the program and registration are details coming soon. Date: 28 & 29 August 2025 Location: ETH Zurich, Main Building #PrecisionMedicine #PersonalizedHealth #FromTechnologytoTreatment2025 #PHRT #SPHN #HealthcareInnovation #Omics #MedicalResearch #Collaboration

Medical Research Needs Collaboration – ETH Zurich’s Efforts to Bridge Research and Clinical Practice   In a recent interview, Christian Wolfrum, Vice President for Research at ETH Zürich, highlighted the importance of enhancing collaboration between medical research and clinical practice.   A major challenge in personalized medicine is the need for large datasets. Initiatives such as the PHRT (Personalized Health and Related Technologies) and the Swiss Personalized Health Network (SPHN) have made remarkable progress, not only in building the necessary data infrastructures but also in developing solutions that are directly applicable to daily medical practice. These initiatives are helping to improve the integration of medical data into research and treatment. International collaborations with institutions such as the Charité - Universitätsmedizin Berlin and Mount Sinai in New York are also essential for expanding the data infrastructure needed for personalized therapies.   While ETH Zurich’s collaboration with hospitals is progressing well, there is still a need for streamlined framework agreements and standardized research contracts to further improve cooperation.   The growing importance of shared data infrastructures and collaborative networks is a step forward in facilitating these efforts.   Read the full interview here: https://lnkd.in/gvFHFTF3

Engineering Meets Medicine: Key Insights from Today's Event Today, we had the privilege of hosting PRiME Next-Generation Precision Medicine at the University of Toronto, a next generation precision medicine institutional strategic initiative for an important discussion on the future of precision and regenerative medicine. Molly Shoichet, Scientific Director of PRiME, provided valuable insights into how engineering and medicine are converging to improve treatments for neurological disorders and cancer. Her lecture highlighted the potential of drug and cell delivery strategies in addressing complex medical challenges. Following the presentation, Prof. Dr. Andreas Wicki from the Experimental Oncology Lab at the Universitätsspital Zürich and Didier Surdez, Head of Tumor Research at Universitätsklinik Balgrist shared their perspectives on the Swiss landscape, offering critical insights into the local challenges and opportunities in advancing precision medicine. This was followed by a lively discussion with experts from ETH Zürich, the Kinderspital Zürich, The LOOP Zurich and others. The conversation focused on building a global collaborative network in precision medicine. Key points included: - Opportunities to leverage regional strengths to establish a unified global approach in precision medicine and drug discovery. - Strategies to overcome challenges in resource-sharing and collaboration. - The importance of cross-sector partnerships between academia, hospitals, and industry. The discussions today emphasized the value of collaboration and how collective efforts can drive meaningful progress in healthcare. A big thank you to everyone who contributed to today’s discussions. We’re looking forward to seeing how these collaborations evolve and the lasting impact they’ll have on medical research and patient care.   #PrecisionMedicine #RegenerativeMedicine #HealthcareInnovation #MedicalResearch #Collaboration

Reminder: Engineering Meets Medicine – Exclusive Event on Precision and Regenerative Medicine In just one week, join us for an exclusive event hosted by PHRT, in collaboration with ETH Zürich, Universitätsspital Zürich, Universitätsklinik Balgrist, Kinderspital Zürich, and Prof. Dr. Molly Shoichet from the University of Toronto! When: January 28, 2025 | 16:00 - 18:30 Where: CAB H41 food&lab, Universitätsstrasse 6, Zürich Find the location on Google Maps: https://lnkd.in/eJ6xNSNT Prof. Dr. Molly Shoichet will share insights on the transformative potential of precision and regenerative medicine, followed by an interactive roundtable discussion with top experts from hospitals, universities, and research institutions. Learn more about the program here: https://lnkd.in/e5Jb-cGr We look forward to seeing you there! #PrecisionMedicine #RegenerativeMedicine #MedicalInnovation #Networking #EngineeringMeetsMedicine #GlobalCollaboration

Dr. Daniel Vonder Mühll is delivering an "Out of the Box" talk titled "What is around us? From Permafrost to Personalized Medicine" at the 1st Peritoneal Research and Technology Summit in Pontresina, Graubünden, Switzerland.   The summit, which has been ongoing since January 15th, focuses on the intricate biology and disease mechanisms within the peritoneal cavity and their clinical implications. By fostering interdisciplinary collaboration among biologists, engineers, and clinicians, it aims to accelerate the understanding of peritoneal biology and develop targeted therapies for diseases such as endometriosis, peritoneal cancer, and complications from abdominal and cardio-thoracic surgery.   A big thank you to all involved for once again making a crucial contribution to the advancement of personalized medicine. The collaborative efforts at this summit continue to drive progress in tailoring healthcare solutions to individual patient needs, improving outcomes, and enhancing the quality of care. https://lnkd.in/eFDFgxJP   #PersonalizedMedicine #PeritonealResearch #MedicalInnovation #PatientCenteredCare #PersonalizedHealthcare

Engineering meets Medicine: exclusive event on Precision and Regenerative Medicine Join us on January 28, 2025, for an exclusive event hosted by PHRT in collaboration with the ETH Zürich, the Universitätsspital Zürich, Universitätsklinik Balgrist and the Kinderspital Zürich and Prof. Dr. Molly Shoichet, Scientific Director of PRiME at the University of Toronto. This special event will feature a compelling talk by Prof. Shoichet on the transformative potential of precision and regenerative medicine. Following the lecture, an interactive roundtable discussion will bring together experts from hospitals, universities, and research institutions to explore the latest advances, challenges and future directions in precision medicine and how to collaborate on a global level. Don’t miss this opportunity to engage with experts in the field. When: January 28, 2025, 16:00-18:30 Where: CAB H41 food&lab, Universitätsstrasse 6, Zürich (Google Maps: https://lnkd.in/eW6u6VSz) Find out more about the program here: https://lnkd.in/e5Jb-cGr #precisionmedicine #phrt #prime #mollyshoichet #personalizedhealth #regenerativemedicine

The ETH PHRT (https://www.sfa-phrt.ch/) Swiss Multi-Omics Center (http://smoc.ethz.ch/) and the University Children's Hospital Zurich (https://lnkd.in/g69siisT) are excited to announce that they have received a Horten Consortium Project for Clinical Translation of 3 million CHF for their proposal "Rapid and Accurate INborn Disease Recognition via multi-Omics Profiling" (RAINDROP). The project aims to leverage multi-omics to enhance diagnostics of Inborn Errors of Metabolism. These rare genetic disorders can be life-threatening, especially in the newborn and early childhood periods, and often incur significant long-term complications. During the three-year project, an interdisciplinary team under the lead of Matthias Baumgartner, Sean Froese, Patrick Pedrioli, Nicola Zamboni, and Sandra Goetze will analyze a substantial number of patient samples from a biobank that have been collected over the past 30 years. By integrating genomic, transcriptomic, proteomic, and metabolomic data, the consortium aims to improve both the speed and accuracy of diagnoses while providing deeper insights into the underlying mechanisms of disease development. We appreciate the generous support of the Helmut Horten Foundation (https://lnkd.in/g5ivzvcY) to realize RAINDROP's translational potential and its importance in advancing precision medicine for children with rare genetic disorders.

Missed the Data for Health symposium? 📊 The #presentations are now available online! Explore insights on personalized health in Switzerland and see how far we've come. 👉 https://lnkd.in/eQbJ2pqG #DataForHealth #PersonalizedHealth #Data4Health2024 #DataForHealth2024 #DataForHealth #PersonalizedHealth #HealthData  PHRT - Personalized Health and Related Technologies, Russ Altman, Karin Frei

🔬 The first #Tumor #Profiler #consortium paper just came out, and Rebekka Wegmann continues her tour-de-force 💫 Here we show that supercharged multi-omic #AML profiling (with up to 9️⃣ OMIC platforms analyzing each patient sample) is possible in a clinically meaningful turnaround time, and highly informative of treatment resistance and options for relapsed/refractory AML patients. Watch this space, there's more to come from the TPC 😉 Clinically led by the wonderful Prof. Alexandre Theocharides and Markus Manz, and including the labs from Bernd Bodenmiller, Bernd Wollscheid, Lucas Pelkmans, Gunnar Rätsch, Mitch Levesque, Viola Heinzelmann-Schwarz, Viktor H. Koelzer, Marina Bacac, Nora C. Toussaint, Andreas Wicki, Holger Moch, Niko Beerenwinkel and over 100 consortium members 🤝! Funding from PHRT - Personalized Health and Related Technologies, Roche, ETH Zürich, University of Zurich, Universitätsspital Basel, Universitätsspital Zürich; Original vision and setup credits to Ruedi Aebersold, Detlef Günther, and others 🏅. 🔗 Paper (open access): https://lnkd.in/eYdJ_brj 🔗 Tumor Profiler consortium: https://lnkd.in/eE8T_4bA

An exciting, varied and highly interesting symposium has come to an end: over 450 participants, more than 30 speakers and numerous supporters have made this event such a success. We would like to express our sincere thanks to all of them. The event symbolized the power of joining forces when different disciplines and institutions work together, share ideas, and collaborate on innovative approaches. The results achieved over the past eight years by the two initiatives, PHRT - Personalized Health and Related Technologies and Swiss Personalized Health Network (SPHN), reflect both impressive successes and existing obstacles that face such collaborative efforts. We are delighted that the efforts of the ETH Domain and the SPHN can contribute to improving the quality of diagnosis, patient treatment, and healthcare. This paves the way for further innovative solutions to be brought to the clinic. #DataForHealth2024 #DataForHealth #PersonalizedHealth #PHRT #SPHN #PersonalizedMedicine #ETHDomain