Tsingke Biotech

🎄 Celebrate the Season with Tsingke: Exclusive Holiday Offer! This holiday season, we’re spreading festive cheer with a special gift for new customers! Get into the spirit of giving with a FREE trial of our high-quality qPCR Probe synthesis service—2 complimentary qPCR probes (up to 35nt), perfect for your research needs. 🎁 Limited-Time Free Trial Details: Type: FAM, BHQ1, FAM, MGB, FAM, TAM, FAM, BIO, C6-NH2, PHO Scale: ≤2OD/5nmol Eligibility: New customers only Duration: Available from Dec 25 to Jan 15 (limited to first 50 customers) Celebrate the season with Tsingke and enhance your research with our trusted solutions. Don’t miss this festive opportunity—contact us today to claim your free trial! 🔗 https://lnkd.in/gD_xpyJg #Tsingke #qPCRProbes #MerryChristmas #FestiveOffer #ResearchMadeEasy

🔬 MGB Probes: A Key Tool in Inspection & Quarantine 🔬 The inspection and quarantine of plants and animals have become critical measures to prevent the spread of viruses and ensure public health. With advancements in breeding and cultivation methods, the threat of viral invasions has grown, making quarantine an essential process for safeguarding ecosystems and human health. 🔬 MGB Probes in Modern Quarantine As one of the most effective tools in the quarantine process, MGB probes enhance pathogen detection, making them invaluable in animal and plant disease control. These probes, known for their high sensitivity and specificity, are essential for the prevention and control of infectious diseases. At Tsingke, our MGB probes are synthesized in a state-of-the-art 100,000-level clean room, ensuring minimal contamination and high purity. Adhering to ISO 13485 standards, we deliver custom, high-quality probes with rigorous quality control. Available in lengths of 13-25 nucleotides, Tsingke’s MGB probes are purified using advanced methods like DSL, OPC, PAGE, and HPLC, ensuring top-tier performance for research and diagnostics. Trusted by over 500 IVD companies, our MGB probes are the ideal choice for reliable, high-precision results. 👉 Get in touch to learn more about how Tsingke’s MGB probes can support your research and enhance your quarantine operations! 🔗 https://lnkd.in/g2JBrCS4 #TsingkeBlog #MGBProbes #InspectionAndQuarantine #MolecularBiology

🎉 Happy New Year from Tsingke! 🎉 As we step into 2025, we reflect on the remarkable journey of the past year and look forward to the exciting opportunities ahead. 🌟 We are deeply grateful for the continued trust and collaboration of our customers and partners. 2024 has been a year of significant progress in technology and customer service, and we couldn’t have achieved it without your unwavering support. ✨ Our commitment to driving innovation and sustainability remains stronger than ever as we aim to not only meet but exceed your expectations. 🌱 Thank you for being an essential part of our journey. Together, let’s embrace the new possibilities that 2025 holds! 🚀 Wishing you a year filled with health, happiness, and success. 🎯 #HappyNewYear #Tsingke #Innovation #Sustainability

🌟 Breakthrough mRNA Therapy Tackles Deadly Pregnancy Condition in Mice Exciting news in mRNA-based therapies! A recent study demonstrates how targeted mRNA therapy can reverse the underlying causes of pre-eclampsia, a life-threatening pregnancy complication. In mice experiments, researchers successfully delivered genomic instructions for a blood-vessel growth factor directly to the placenta, stimulating the production of extra blood vessels and lowering high blood pressure—a key symptom of pre-eclampsia. This condition is responsible for 15% of maternal deaths and 25% of fetal and newborn deaths globally. While still in early stages and requiring human trials, this research holds great promise for pre-eclampsia treatment and could pave the way for broader applications of mRNA-based therapies in maternal health. 🌱 This study highlights the potential of mRNA technology far beyond vaccines—demonstrating its ability to address complex, life-threatening conditions. Stay tuned for more groundbreaking innovations! 🚀 🔗 https://lnkd.in/gDaeWXuR #TsingkeInsights #mRNA #PregnancyHealth #PreEclampsia #MedicalInnovation

🌟 World-First Stem-Cell Treatment Restores Vision in People! 👁️ In a groundbreaking study published in The Lancet, a stem-cell-based treatment has successfully restored vision in individuals with damaged corneas. Four participants with severe vision impairment received transplants made from reprogrammed stem cells, with three showing substantial improvements that lasted over a year. The procedure, which involves transforming blood cells into corneal epithelial cells, offers a promising alternative to traditional corneal transplants, which have uncertain outcomes and higher rejection risks. Importantly, no serious side effects or immune rejection were observed in the participants. This exciting development opens new possibilities for treating limbal stem-cell deficiency (LSCD), a condition that causes blindness due to corneal damage. While the results are promising, further trials are needed to confirm the long-term efficacy and safety of this stem-cell treatment. “We are headed in the right direction,” says Kapil Bharti, a leading stem-cell researcher. As clinical trials continue, this breakthrough could pave the way for innovative treatments for eye diseases worldwide. 🔗 https://lnkd.in/g6JrmbFm #TsingkeInsights #StemCellTherapy #VisionRestoration #MedicalInnovation

🔍 #TsingkeFAQTime: Exploring Gene Overexpression: Key Methods and Applications Gene overexpression is a powerful technique used to study gene function and develop therapeutic strategies. Here are the most common methods for gene overexpression: 🔬 Overexpression Plasmids: A straightforward approach where the target gene is introduced into cells via plasmid transfection, leading to increased gene expression. 🧬 Overexpression Lentivirus: Lentiviral vectors are used to stably integrate the target gene into the host genome, ensuring long-term expression—ideal for permanent modifications or continuous gene expression. 🧪 CRISPRa Transcriptional Activation System: CRISPR-based technology allows precise activation of endogenous genes, offering fine-tuned control over gene expression with high specificity. Each method has unique strengths, and the best choice depends on your experimental objectives and the cell types you're working with. Which method do you use in your research? Let's discuss it! https://lnkd.in/gD_xpyJg #Tsingke #GeneOverexpression #Biotechnology #CRISPR

🚀 The Future of IVT mRNA Technology: Revolutionizing Biopharma The success of mRNA vaccines, especially against COVID-19, has accelerated the adoption of IVT mRNA across research and industry. In 2023, Nobel laureates Katalin Karikó and Drew Weissman were recognized for their groundbreaking work on mRNA, further validating its transformative potential. Key Applications of IVT mRNA 🔬 Research: Gene function studies, CRISPR gene editing, protein production 💉 Vaccine Development: Infectious disease vaccines, cancer immunotherapy, mRNA-based vaccines 🧬 Gene Therapy: Protein replacement, immunotherapy, and regenerative medicine Innovations Driving the Industry IVT mRNA technologies like saRNA and circRNA are advancing the precision medicine frontier. With self-amplification and greater stability, they offer groundbreaking solutions for treating complex diseases. Tsingke's Role in Advancing mRNA Solutions As a leading enterprise in the field of DNA and RNA synthesis, Tsingke leverages its comprehensive gene synthesis supply chain and advanced IVT mRNA synthesis platform to meet diverse needs from small-scale research to large-scale production. We not only provide high-quality IVT mRNA synthesis services but also optimize sequences, select modifications, and customize delivery plans based on specific application scenarios, ensuring optimal performance in vaccine development, gene therapy, and other fields. 🌐 Let's innovate for a healthier future! 🔗 https://lnkd.in/gpvaZ_JN #Tsingke #IVTmRNA #mRNA #GeneTherapy #VaccineDevelopment

🧬 Our team had the privilege of presenting Tsingke's cutting-edge capabilities at the Cold Spring Harbor Asia (CSHA) Conference in Awaji, Japan, focusing on "Preparing for the Next Pandemic: Evolution, Pathogenesis, and Virology of Coronaviruses." 🌍 This global gathering of top virologists and immunologists explored critical research on coronaviruses. As a leader in synthetic biology, Tsingke showcased our comprehensive platform for coronavirus research. With over 20 years of experience in oligo synthesis, we have built GMP-standard production labs, certified with ISO13485, ensuring our oligos meet the highest standards of sensitivity, stability, and contamination-free results—all essential for accurate viral detection. 🧬 During the COVID-19 pandemic, we played a pivotal role in supporting over 20 national institutions, including the Chinese CDC, by helping mass-produce nucleic acid test kits to meet the urgent demands of millions. 🦠 Our virus packaging platforms—lentivirus, adenovirus, and AAV—are vital for vaccine and drug development, ensuring effective gene expression and immune response. We also provide functional pseudoviruses for neutralizing antibody testing, which supports the evaluation of immune responses in vaccine research. 🔬 With these innovative solutions, Tsingke continues to drive the development of next-generation vaccines and therapeutics. Stay tuned for more exciting updates from our team! 🚀 #Tsingke #CoronavirusResearch #CSHA2024 #ViralPackaging #SyntheticBiology

Elevating Gene Delivery with Tsingke Virus Packaging Services🚀 At Tsingke, we are at the forefront of cutting-edge viral packaging technology, a vital tool in gene therapy, gene function research, and vaccine development. Our advanced viral packaging services utilize the natural mechanisms of viruses to efficiently deliver foreign genes into target cells, offering precision and reliability in biomedical research. We are proud to provide high-quality packaging services for Lentivirus (LV), Adenovirus (ADV), Adeno-Associated Virus (AAV), and customized pseudoviruses—all backed by our GMP-like standard biosafety Level 2 (BSL-2, P2) laboratory. Why Choose Tsingke for Your Virus Packaging Needs? 🔬 High Titer: Our efficient lentivirus packaging system ensures a titer ≥1 × 10⁸ TU/mL, providing robust results for your experiments. 💎 High Purity: Using ultracentrifugation and filtration techniques, we deliver in vivo-grade purity to meet the highest standards of research. ⏱️ Ultra-Fast Turnaround: With gene synthesis and virus packaging delivered in as little as 15 days, Tsingke provides fast, reliable service without compromising on quality. Unlock the Power of Virus Packaging with Tsingke! Start your project today and save $20 on orders over $100 with our exclusive limited-time offer! Don't miss out – take advantage of this deal now! https://lnkd.in/gq5Kn3nB #Tsingke #VirusPackaging #GeneTherapy #AAV

🚀 DeepMind Releases Full Code for AlphaFold3! 🧬 After six months of anticipation, DeepMind has made good on its promise to release the full computational model behind AlphaFold3, the latest version of its AI-powered protein structure prediction tool. Available on GitHub for noncommercial use, this release enables the global research community to directly engage with the model, pushing forward biomedical discoveries and drug development. AlphaFold3's ability to predict protein structures and interactions with DNA, RNA, and other proteins has already made waves in drug discovery. With this release, researchers can now experiment with the AI, build upon it, and contribute to its growth. Despite a delayed release, the research community is excited. "The model and weights are of huge importance for evaluation and further progress," says Stephanie Wankowicz, a computational biologist at Vanderbilt University. This public release opens the door for even more breakthroughs in AI-driven biosciences. We can't wait to see how researchers will leverage this powerful tool for future innovations! 🔗 https://lnkd.in/egpR5fN3 #TsingkeInsights #AlphaFold3 #ProteinPrediction #DrugDiscovery