Ascenion GmbH

We wish you a Merry Christmas and a relaxing holiday season, enjoy the time with your loved ones! Your Ascenion Team 💗

Last week our colleagues Stefanie Possekel, Esther Maria Lange and Rebecca Engels had the pleasure to close our conference year by attending BioFIT Event in #Lille and present our #technology #portfolio. They especially enjoyed the insightful panel discussions, learning from the experience of experts across various fields. Looking forward to the upcoming #conferences in #2025 and a productive year ahead!

Only one week left to register! ⏰ ➡️ https://lnkd.in/dxwfmazS

Meet our colleagues Esther Maria Lange, Rebecca Engels and Stefanie Possekel at #Biofit in #Lille next week and explore our portfolio of technologies from our partner institutes, that are available for in-licensing and co-development! #Biofit #MedFIT #MEDigIT #lifesciences #networking

#TechnologyTuesday 𝗔𝗻 𝗲𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗲𝗱 𝘀𝗲𝗿𝗶𝗻𝗲 𝗶𝗻𝘁𝗲𝗴𝗿𝗮𝘀𝗲 𝗳𝗼𝗿 𝘁𝗮𝗿𝗴𝗲𝘁𝗲𝗱 𝗴𝗲𝗻𝗲 𝘁𝗿𝗮𝗻𝘀𝗳𝗲𝗿 𝗶𝗻 𝗵𝘂𝗺𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 🔺#Genome #editing #tools like #CRISPR-Cas are revolutionary but have limitations in transferring large genetic information. 💡 A new #serine #integrase variant, #ePa01, has been developed at Charité - Universitätsmedizin Berlin to overcome the size limitations of viral systems and reduce costs associated with GMP-grade viruses. This variant offers a promising alternative for precise, site-specific integration of large DNA cargo and can serve as a powerful #tool to develop advanced #cell and #gene #therapies that require #large #cargo #delivery, but also other #biotechnology solutions such as #cell line #engineering. 👩🔬 👨🔬 Inventors: Dimitrios Laurin Wagner, Isabell Kassing, Daniel Ibrahim, Jonas Kath 🔎 Learn more about this #technology on our website: https://lnkd.in/da-cBppc #SerineIntegrase #GeneTherapy #GenomeEditing #GeneTransfer #ATMP #CellLineEngeneering

#TechnologyTuesday 𝗕𝗮𝘀𝗲 𝗲𝗱𝗶𝘁𝗶𝗻𝗴 𝗲𝗻𝘇𝘆𝗺𝗲𝘀 𝗳𝗼𝗿 𝗺𝘂𝗹𝘁𝗶𝗽𝗹𝗲𝘅 𝗲𝗱𝗶𝘁𝗶𝗻𝗴 𝘄𝗶𝘁𝗵 𝘀𝗶𝗺𝘂𝗹𝘁𝗮𝗻𝗲𝗼𝘂𝘀 𝗴𝗲𝗻𝗲 𝗸𝗻𝗼𝗰𝗸-𝗶𝗻 𝗮𝗻𝗱 𝗸𝗻𝗼𝗰𝗸-𝗼𝘂𝘁 🔺 Developing successful cell therapies is challenging due to the complexity and cost associated with multiple platforms and processing steps. The #BEKI gene editing strategy offers a solution by combining knock-in and knock-out techniques to reduce toxicity and off-target effects, resulting in a safer and more cost-effective option for cell therapy development. 💡 The novel non-viral Base Editor Knock-In (#BEKI) #genome #editing strategy developed by Dimitrios Laurin Wagner, Viktor Glaser and Jonas Kath at Charité - Universitätsmedizin Berlin allows for complex gene editing reactions in a single transfection reaction by simultaneously linking a knock-in with knock-out using a nickase-base editor fusion protein and several single guide RNAs. 🔎 Learn more about this #technology on our website: https://lnkd.in/dwsz6yBG #BaseEditors #GeneEditingTool #CellandGeneTherapies #CARTcells #Autoimmunity #AllogeneicCellTherapy

Streamlining the foundation of life science spin-offs: TransferAllianz e.V. publishes #guidelines for standardized licensing terms to support fair and transparent commercialization with internationally proven benchmarks. https://lnkd.in/dkQDNuBS #TechnologyTransfer #SpinOffs #LifeSciences #Innovation #Startups #LicensingTerms #Commercialization

#WEBINAR ALERT 📢 𝗙𝗿𝗼𝗺 𝗟𝗶𝗳𝗲 𝗦𝗰𝗶𝗲𝗻𝗰𝗲𝘀 𝗶𝗻𝘁𝗼 𝗕𝘂𝘀𝗶𝗻𝗲𝘀𝘀 - 𝗔 𝗚𝗢-𝗕𝗶𝗼 𝗶𝗻𝗶𝘁𝗶𝗮𝗹 𝗜𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻 𝗪𝗲𝗯𝗶𝗻𝗮𝗿 𝗯𝘆 𝗔𝘀𝗰𝗲𝗻𝗶𝗼𝗻 Join us on 𝗗𝗲𝗰𝗲𝗺𝗯𝗲𝗿 𝟲, 𝟭𝟭 𝗮𝗺 - 𝟭𝟮.𝟯𝟬 𝗽𝗺 (CET) to gain valuable insights on the GO-Bio initial funding programme for innovative ideas in early stages of development! ⭐ Learn everything you need to know about the GO-Bio initial funding programme and get your questions answered right away! ⭐ Listen to a GO-Bio initial Success Story and first-hand experiences with the GO-Bio initial funding programme. ⭐ Have a chat and expand your network in our networking session at the end of the webinar. 👉 Register now: https://lnkd.in/dxwfmazS 🎁 Bonus: For every participant, we donate one Euro to the organisation Ozeankind, which is committed to environmental education and recycling projects for children. #webinar #GOBioinitial #lifesciences #innovation #network ------------------------------ The Life Science Digital Hub project is funded by the German Federal Ministry of Education and Research as part of the GO-Bio initial programme. Funding reference: 16LW0585.

#TechnologyTuesday 𝗥𝗮𝗽𝗶𝗱, 𝘀𝗶𝗺𝘂𝗹𝘁𝗮𝗻𝗲𝗼𝘂𝘀 𝗮𝗻𝗱 𝗻𝗼𝗻-𝗱𝗲𝘀𝘁𝗿𝘂𝗰𝘁𝗶𝘃𝗲 𝗯𝗹𝗼𝗼𝗱 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀 𝘂𝘀𝗶𝗻𝗴 𝗮 𝗺𝘂𝗹𝘁𝗶-𝗼𝗺𝗶𝗰𝘀 𝗡𝗠𝗥 𝗽𝗹𝗮𝘁𝗳𝗼𝗿𝗺 🔺 #Blood #analysis is the glod-standard in #clinical #diagnostic, despite the fact that traditional methods for determining #serum #concentrations of acute-phase #proteins are requiring individual tests for each protein, influenced by protein #glycosylation, and destructive to the sample. This hampers our understanding of #disease #mechanisms and the formulation of #targeted #therapies. 💡 Researchers at the Universität zu Lübeck have developed a #novel multi-omics #NMR-based approach that enables #simultaneous #quantification and #profiling of all relevant blood proteins and their glycosylation in a single, swift measurement. This non-destructive, cost-effective method provides comprehensive #insights into #protein #glycosylation and #lipidation, enhancing #diagnostic #accuracy and potentially leading to more effective #treatment #strategies. 👩🔬 👨🔬 Inventors: Ulrich Günther, Alvaro Mallagaray de Benito, Lorena Rudolph, Melissa Lindloge 🔎 Learn more about this #technology: https://lnkd.in/dhjAAia4 #NuclearMagneticResonance #Nglycans #SignalSelection #Inflammation, #HeartDisesase

We had a great time at #BioEurope in #Stockholm! The event was excellently organised, allowing us to have many productive meetings focused on our #portfolio #technologies from our partner institutes. As every year, the numerous evening events provided great opportunities to reconnect with old friends and make new #contacts. Stockholm’s beautiful locations added the cherry on top, making the events even more memorable and enjoyable. We are sure it will be just as good next year when #BioEurope will take place in #Vienna at the home of our friends from LISAvienna! We are already looking forward to it! #TechnologyPortfolio #StartupPortfolio #Networking #LicencingOpportunitys