DZHK Deutsches Zentrum für Herz-Kreislauf-Forschung e. V.

🏆 13 DZHK researchers named in the Clarivate #HighlyCitedResearchers2024 list! We're proud of this scientific expertise within the DZHK, serving patients and international #cardiovascular research. https://lnkd.in/eCSQhWn3 These scientists have demonstrated broad influence in their field of research: 𝐓𝐡𝐞𝐲 𝐚𝐫𝐞 𝐚𝐦𝐨𝐧𝐠 𝐭𝐡𝐞 𝐨𝐧𝐞 𝐩𝐞𝐫 𝐜𝐞𝐧𝐭 𝐨𝐟 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐜𝐢𝐭𝐞𝐝 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐢𝐧 𝐭𝐡𝐞𝐢𝐫 𝐟𝐢𝐞𝐥𝐝 𝐨𝐯𝐞𝐫 𝐭𝐡𝐞 𝐩𝐚𝐬𝐭 𝐝𝐞𝐜𝐚𝐝𝐞. Congratulations to 🤝 👉Ackermann, Lutz | Georg-August-Universität Göttingen | 🧪Chemistry 👉Andreas Daiber | Johannes Gutenberg-Universität Mainz | 🖇Cross-Field 👉 Martin Dichgans | Ludwig-Maximilians-Universität München |🖇Cross-Field 👉Stefanie Dimmeler | Goethe-Universität Frankfurt | 🖇Cross-Field 👉Sofia Kirke Forslund-Startceva | Max Delbrück Center | 🧫Biology and Biochemistry 👉Uwe Haberkorn | Universität Heidelberg | 🩺 Clinical Medicine 👉Paulus Kirchhof | Universitätsklinikum Hamburg Eppendorf | 🖇Cross-Field 👉Matthias Mann | Max Planck Institute of Biochemistry | 🧫Biology and Biochemistry, 🧬Molecular Biology and Genetics 👉Thomas Muenzel | Johannes Gutenberg-Universität Mainz |🖇Cross-Field 👉Stefan Offermanns | Max Planck Institute for Heart and Lung Research |🖇Cross-Field 👉Nikolaus Rajewsky | Max Delbrück Center |🧬Molecular Biology and Genetics 👉Fabian Theis | Technische Universität München | 🧫Biology and Biochemistry, 🧬Molecular Biology and Genetics 👉Holger Thiele | Universität Leipzig | 🩺 Clinical Medicine #HighlyCited2024 📈 According to data from the Web of Science and qualitative analysis by experts at the Institute for Scientific Information (ISI).

7-6-5-4-3-2-1 The countdown is on! On 22 November, it's that time again: another edition of our popular Science on Friday series will focus on 𝐒𝐞𝐱 𝐚𝐧𝐝 𝐠𝐞𝐧𝐝𝐞𝐫 𝐢𝐧 𝐜𝐚𝐫𝐝𝐢𝐨𝐯𝐚𝐬𝐜𝐮𝐥𝐚𝐫 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 22/11/2024, 4-5 pm (CET), online (via zoom), https://lnkd.in/ekm_EGSt Don't miss out on the chance to hear these great speakers! ✔Sex differences in cardiovascular inflammation and disease manifestation: insights from preclinical research | Sabine Steffens (Munich) ✔Sex differences in coronary atherosclerotic phenotype and healing pattern on optical coherence tomography imaging | Lena Marie Seegers (Frankfurt) ✔Sex and age characteristics in acute or chronic myocarditis: a descriptive, multicenter cohort study | Bettina Heidecker (Berlin) ✔Gender equity as a basis for excellence in health care | Carolin Lerchenmüller (Heidelberg + Zürich) chaired by Daniel Andergassen (Munich), David M. Leistner (Frankfurt) & Sophie Van Linthout (Berlin) DZHK members will be invited by email 📧 & receive a registration link. The registration link is also available on the DZHK intranet (https://lnkd.in/eGRYzhD5, login required). All others: write to info@dzhk.de #SexAndGenderMedicine #GenderMedicine #WomensHealth #SexDifferences #GenderEquality #HealthcareGap

Sehr verdiente Auszeichnung für die Teams der DZHK-Standorte Niedersachsen und Nord. So geht Translation! 👏🏻🔬🧑🔬👩🏻🔬👨🔬❤️🩹

Don´t miss our next Science on Friday webinar: 𝐓𝐢𝐬𝐬𝐮𝐞 𝐞𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠 𝐟𝐨𝐫 𝐫𝐞𝐩𝐚𝐢𝐫 𝐨𝐟 𝐭𝐡𝐞 𝐜𝐚𝐫𝐝𝐢𝐨𝐯𝐚𝐬𝐜𝐮𝐥𝐚𝐫 𝐬𝐲𝐬𝐭𝐞𝐦 🫀🔧 25/10/2024, 4-5 pm (CET), online (via zoom) DZHK members will be invited by email 📧 & receive a registration link. The registration link is also available on the DZHK intranet (https://lnkd.in/eeqiu2_Y, login required). All others: write to info@dzhk.de Happy to have these wonderful speakers: 💙 Disease modelling in human cardiac #organoids | Jaya Krishnan (Frankfurt) 💚 Advanced heart-forming organoids for modeling human multi-organ development | Lika Drakhlis (Hannover) 💛 Incorporating immune cells in heart-on-a-chip to mimic inflammation and drive vascularization | Milica Radisic (Toronto) chaired by Alessandra Moretti (Munich) & Wolfram Zimmermann (Göttingen) https://lnkd.in/efxktGDr #BiomedicalEngineering #TissueEngineering #ArtificialOrgans

𝗘𝗶𝗻 𝗔𝗯𝘀𝗰𝗵𝗶𝗲𝗱 𝗻𝗮𝗰𝗵 𝟮𝟲 𝗝𝗮𝗵𝗿𝗲𝗻 𝗯𝗮𝗵𝗻𝗯𝗿𝗲𝗰𝗵𝗲𝗻𝗱𝗲𝗿 (𝗛𝗲𝗿𝘇-)𝗙𝗼𝗿𝘀𝗰𝗵𝘂𝗻𝗴 𝘂𝗻𝗱 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻. Nach mehr als zwei Jahrzehnten herausragender Leistungen verabschiedet sich Prof. Dr. Gerd Hasenfuß, Direktor der Klinik für Kardiologie und Pneumologie und Vorsitzender des Herzzentrums der Universitätsmedizin Göttingen (UMG), in den wohlverdienten Ruhestand. Am 18. Oktober 2024 hält er seine Abschiedsvorlesung zum Thema „Interaktion und Innovation“ und blickt auf eine beeindruckende Karriere zurück. Seit 1998 leitete Prof. Hasenfuß die Klinik und das von ihm mitbegründete Herzzentrum der UMG, das heute zu den besten Spezialzentren weltweit zählt. Sein Forschungsschwerpunkt lag auf Herzinsuffizienz, einer der weltweit führenden Ursachen für Herzerkrankungen. Er trug maßgeblich zur Entdeckung neuer molekularer Mechanismen bei, die die Krankheitsentstehung beeinflussen, und entwickelte innovative Therapieansätze – darunter das „InterAtrial Shunt“-Verfahren zur Behandlung der diastolischen Herzinsuffizienz. 🫀 𝗪𝗲𝗴𝗯𝗲𝗿𝗲𝗶𝘁𝗲𝗿 𝗶𝗻 𝗱𝗲𝗿 𝗛𝗲𝗿𝘇-𝗞𝗿𝗲𝗶𝘀𝗹𝗮𝘂𝗳-𝗙𝗼𝗿𝘀𝗰𝗵𝘂𝗻𝗴: Prof. Hasenfuß koordinierte den Sonderforschungsbereich „Modulatorische Einheiten bei Herzinsuffizienz“ und war Gründungsmitglied des DZHK Deutsches Zentrum für Herz-Kreislauf-Forschung e. V. Während seiner Zeit als Vorsitzender der Deutsche Gesellschaft für Innere Medizin e.V. ebnete er den Weg für die Initiative „Klug entscheiden“, die die medizinische Versorgung nachhaltig verbessern soll. 🏅 𝗔𝘂𝘀𝗴𝗲𝘇𝗲𝗶𝗰𝗵𝗻𝗲𝘁𝗲 𝗞𝗮𝗿𝗿𝗶𝗲𝗿𝗲: Für sein Lebenswerk erhielt er 2024 die Leopold-Lichtwitz-Medaille, die höchste Auszeichnung der DGIM. Prof. Hasenfuß hat in seiner Karriere nicht nur wissenschaftliche Maßstäbe gesetzt, sondern auch die klinische Versorgung im Bereich der Herzmedizin revolutioniert. Wir danken Prof. Hasenfuß für seine herausragende Arbeit in der Herzmedizin und wünschen ihm alles Gute für die Zukunft! Die Vorlesung findet am 18. Oktober 2024 ab 14:00 Uhr im Hörsaal 81 der Universitätsmedizin Göttingen statt. 📸 Foto: Karsten Thormaehlen

Eins der Focusthemen 2025: 🫀 Herz-Kreislauf- und Stoffwechselerkrankungen

𝐓𝐢𝐧𝐲 𝐑𝐍𝐀𝐬 𝐰𝐢𝐭𝐡 𝐩𝐫𝐨𝐟𝐨𝐮𝐧𝐝 𝐩𝐡𝐲𝐬𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐢𝐦𝐩𝐨𝐫𝐭𝐚𝐧𝐜𝐞 The discovery of these small molecules offers the opportunity to develop new therapies, also for cardiovascular medicine. 🫀🔬💉   The 2024 Nobel Prize in Physiology or Medicine was awarded jointly to Victor Ambros and Gary Ruvkun for the 𝐝𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐲 𝐨𝐟 𝐦𝐢𝐜𝐫𝐨𝐑𝐍𝐀 𝐚𝐧𝐝 𝐢𝐭𝐬 𝐫𝐨𝐥𝐞 𝐢𝐧 𝐩𝐨𝐬𝐭-𝐭𝐫𝐚𝐧𝐬𝐜𝐫𝐢𝐩𝐭𝐢𝐨𝐧𝐚𝐥 𝐠𝐞𝐧𝐞 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧. MicroRNA regulation, first discovered by Ambros and Ruvkun, has been functioning for hundreds of millions of years, facilitating the evolution of more complex organisms. Genetic research shows that proper development of cells and tissues depends on microRNAs and abnormal regulation can contribute to cancer. Mutations in microRNA-coding genes have been linked to conditions in humans, including congenital hearing loss, and eye and skeletal disorders. Additionally, mutations in a protein essential for microRNA production lead to DICER1 syndrome, a rare but serious condition associated with cancer in multiple organs and tissues.   MicroRNAs also play an essential role in normal heart development and function; dysregulation can lead to structural deficits and impaired function of the heart. 𝐇𝐞𝐫𝐞'𝐬 𝐚 𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐨𝐧 𝐨𝐟 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐟𝐢𝐧𝐝𝐢𝐧𝐠𝐬 𝐨𝐟 𝐃𝐙𝐇𝐊 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐰𝐨𝐫𝐤𝐢𝐧𝐠 𝐨𝐧 𝐦𝐢𝐜𝐫𝐨𝐑𝐍𝐀𝐬: - the role of miR-206 in artheriosclerosis 👉 https://lnkd.in/eTrJGHAE - microRNA therapy with antimiR-92a 👉 https://lnkd.in/ePZZ-n67 - miR-126-5p protecting vascular integrity 👉 https://lnkd.in/e7MzrGNM - miR-29 in heart fibrosis 👉 https://lnkd.in/ekPY_PP7  photo credit: AdobeStock_532133575

🤯👉🌞𝐈𝐦𝐚𝐠𝐢𝐧𝐞 𝐢𝐭'𝐬 𝐍𝐨𝐯𝐞𝐦𝐛𝐞𝐫, 𝐲𝐨𝐮𝐫 𝐛𝐫𝐚𝐢𝐧 𝐢𝐬 𝐚𝐬 𝐮𝐧𝐢𝐧𝐬𝐩𝐢𝐫𝐞𝐝 𝐚𝐬 𝐭𝐡𝐞 𝐬𝐤𝐲 𝐨𝐮𝐭𝐬𝐢𝐝𝐞, 𝐚𝐧𝐝 𝐲𝐨𝐮 𝐜𝐨𝐮𝐥𝐝 𝐫𝐞𝐚𝐥𝐥𝐲 𝐝𝐨 𝐰𝐢𝐭𝐡 𝐚 𝐫𝐚𝐲 𝐨𝐟 𝐡𝐨𝐩𝐞. 𝐖𝐞𝐥𝐥, 𝐰𝐞'𝐯𝐞 𝐠𝐨𝐭 𝐢𝐭! 👋🎒🧳Leave your lab or clinic behind for two days and immerse yourself in an event designed for anyone serious about #TranslationalResearch. We're thrilled to invite all young researchers from the German Centers for Health Research (DZG) to join us in Potsdam (near Berlin) on 7 and 8 November! Don't miss out on the DZG Science & Career Day! 👉 𝐓𝐫𝐚𝐧𝐬𝐥𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞 – 𝐅𝐫𝐨𝐦 𝐋𝐚𝐛 𝐭𝐨 𝐋𝐢𝐟𝐞: 𝐇𝐨𝐰 𝐭𝐨 𝐓𝐫𝐚𝐧𝐬𝐥𝐚𝐭𝐞 𝐲𝐨𝐮𝐫 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐢𝐧𝐭𝐨 𝐌𝐞𝐝𝐢𝐜𝐚𝐥 𝐈𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐨𝐧𝐬 𝐑𝐞𝐠𝐢𝐬𝐭𝐞𝐫 𝐛𝐲 30 𝐒𝐞𝐩𝐭𝐞𝐦𝐛𝐞𝐫 𝐭𝐨 𝐬𝐞𝐜𝐮𝐫𝐞 𝐲𝐨𝐮𝐫 𝐬𝐩𝐨𝐭! https://lnkd.in/eAb5K8zR Here's what you can look forward to: 📌Young researchers from different disciplines are coming together in one place: We've got cardiologists, lung and cancer researchers, diabetes experts, infection scientists and experts in neurodegenerative and mental illnesses. 📌Glimpses from cell & gene therapy research with Nico Lachmann #MacrophageEnthusiast & Annette Künkele #CARTCellTherapy & Henrik Semb #StemCell 📌From researcher to entrepreneur with Zinecker Heidi & Michael Karle 📌Evening event with the opportunity to practise a scientific pitch in front of an interdisciplinary audience: the stage is all yours for 5 minutes

Ready to take your career to the next level? 🚀 Don't miss this exclusive event designed to inspire and empower your growth. Join us and unlock new opportunities!

📣 The Global Cardiovascular Research Funders Forum (GCRFF), of which the DZHK is a member, proudly announces the launch of the International Research Challenge on Women’s Cardiovascular Health. This unique network grant will provide up to $10 million over five years to address critical gaps in women’s cardiovascular health research. It offers a chance for global, multi-disciplinary collaboration among top scientists. 👉 Letters of intent (LOI) are due by January 15, 2025. 👉 For more information and to apply, visit https://lnkd.in/eb6PP6Hk