Enzymicals AG

🌍 Scale-up of Antibiotic-Free Enzyme Production At Enzymicals, we’re proud to champion environmentally friendly catalyst production. Our latest achievement: scaling up enzyme production using the innovative Gen-H system to 800 liters — all while staying true to our commitment to sustainability. Statement from Dr. Henrike Brundiek, Head of R&D at Enzymicals: “This achievement reflects our team's dedication to pushing the boundaries of antibiotic-free production while maintaining the highest standards of efficiency and quality. By applying Gen-H cutting-edge technology at manufacturing scale, we’re demonstrating that large-scale enzyme production can be both economically viable and ecologically responsible. At Enzymicals, we are committed to being 'green to the last detail' and delivering solutions that meet the growing global demand for sustainable biotechnologies. We also extend our sincere gratitude to our Custom Manufacturing Organization, whose expertise and robust handling of the Gen-H system played a pivotal role in ensuring this scale-up was executed perfectly. Every step of our production process is designed to minimize impact on the planet while delivering high-quality enzymes for industrial applications.“ 📢 Let’s build a greener future together. Contact us to learn how our green biocatalysis solutions can support your production needs. #GreenBiotech #SustainableCatalysis #AntibioticFree #Biocatalysis #EnzymeProduction #Innovation #Sustainability #Biotechnology #ScaleUp Gen-H Genetic Engineering Heidelberg GmbH

🌟 A New Era of Guidance for Enzymicals AG! 🌟 Today marks an exciting milestone for Enzymicals AG as the Supervisory Board met in person for the first time in its new constellation following the recent change in shareholder structure. The board now comprises: •Prof. Uwe Bornscheuer, a globally recognized leader in biocatalysis, co-founder of Enzymicals, and a driving force behind innovation in the field. •Prof. Dagmar Braun, physician, successful entrepreneur in the pharmaceutical industry, and recipient of the prestigious Federal Cross of Merit. •Dr. Martin Erhardt, the newest addition of the board, a pharmacist with extensive expertise in managing pharmaceutical plants and CEO of HERBRAND PharmaChemicals GmbH . This distinguished board will work closely with our CEO, Dr. David Liese, to guide Enzymicals AG through its next phase of growth. During today’s meeting, the board approved significant new investments to drive the company’s continued expansion and success. We are grateful for their insights and leadership as we push forward in revolutionizing enzyme-based solutions for sustainable chemical production. #Enzymicals #Leadership #Biocatalysis #Innovation #Growth

Indeed! Our R&D activities, such as the upPE-T Project and PET-Rezya, are making meaningful contributions to solving the plastic waste problem. For those interested in this work, our senior scientist, Dr. Friedemann Leipold, gives an insightful lecture during the conference – Plastic biodegradation: the next chapter in upcycling through enzymatic biocatalysis. He explain who we enzymatically degrade PET on a kilogram scale to transform it into usable products. Additionally, he discusses fundamental findings to the chemo-enzymatic degradation of polyethylene, which we had in partnership with Uwe Bornscheuer and Ren Wei from the University of Greifswald. His talk is available online here: https://lnkd.in/dimHscBj

Process engineering for enantioselective Michael addition. We’re happy to have Veronika Chadimová with us at Enzymicals for her three-month industrial secondment as part of the CC-TOP Biocatalysis MSCA Research Program! Her focus is on scaling up and intensifying 4-Oxalocrotonate tautomerase reactions targeting the efficient production of valuable GABA precursors. During her stay in Greifswald, Veronika work under the guidance of Philipp Süss who introduce her to optimizing and scaling up enzymatic reactions by the use of Enzymicals equipment infrastructure. Following her initial work at University of Groningen (Gerrit Poelarends) and first secondment at University of Zagreb (Zvjezdana Findrik Blazevic ) she now is engaged to produce relevant quantities of her target enzymes and products. Though winter is settling in around Greifswald, Veronika is enjoying the seasonal charm of our university city — and possibly the occasional cup of hot spiced wine! 🍷 #enzymes #biocatalysis #sustainability #innovation #biotechnology #greenchemistry #catalysis #ProcessChemistry

Enzymicals has announced the appointment of Dr David Liese as its new Chief Executive Officer, following a long-planned succession programme. Dr Liese will replace Dr Erik de Vries, who announced his intention to retire from Enzymicals earlier this year. More information: https://lnkd.in/dVaAg-vG

We're excited to share our latest publication in Food Chemistry, developed with the MACBETH project consortium! The study, Modeling of enzymatic transesterification for omega-3 fatty acids enrichment in fish oil by M. Ongis et al., details how enzyme-based transesterification enrich omega-3 fatty acids, specifically EPA and DHA. The study assesses a kinetic model for transesterification with varying enzyme load and ethanol concentration, which improves ω3 mass fraction in acylglycerols from 35% to 52%. The process was carried out in our flow reactor at a throughput of 1.5 L per hour, catalysed by an enzyme immobilised by ChiralVision BV, easily producing over 100 kg of product! This paves the way for sustainable and efficient omega-3 enrichment processes. Read the paper: https://lnkd.in/dKHBGGeB Curious to learn more? Contact us today and discover how Enzymicals can support your next innovation! #biocatalysis #greenchemistry #foodchemistry #enzymes #BiotechInnovation #EnzymeTechnology #Sustainability Enzyme Technology Alliance

Day two of CPhI. We’ve had many meetings already, but also walked many miles. From Hall 2 to Hall 24 is more than a km! Make the trip out here - 24D72.

Enzymicals invites you to meet our experts, represented by Rainer Wardenga and Christin Peters at booth 24D72 at CPHI from 8th to 10th October 2024. Let us inspire you on how we can support your concepts in the field of industrial biocatalysis.

🔬 IP Licensing opportunity from Enzymicals! 🔬 Enzymicals has a recently granted US and EU patent for the production of chiral amines via transaminase reactions with salt precipitation. This in-situ product crystallization technology marks a breakthrough in the enzymatic synthesis of chiral amines, requiring only equimolar quantities of the amine donor, with the added benefit of product isolation through simple filtration. Independently and successfully demonstrated by various companies and universities at scales of up to 100 kg, this proprietary technology is now available for licensing or outright acquisition. Let’s explore this exciting opportunity at CPHI Milan! Visit us at Booth 24D72 in the Fine Chemicals Zone, and learn how this process can benefit your operations. #Patent #ChiralAmines #Transaminase #CPHI2024 #FineChemicals #SustainableChemistry #Innovation #GreenChemistry #CPHI

🔄 Enzyme-Catalyzed Ester/Amide Transformation: Precision Green Chemistry🧪 The third article in our series on enzyme-catalysed chemical transformations provides some insights into selective enzyme-catalysed ester and amide transformations of small molecules. Enzymes such as lipases, amidases, proteases and esterases are well known and widely used in industry due to their exceptional enantioselectivity, regio- and chemoselectivity. They can be used in synthesis, resolution, hydrolysis, alcoholysis and transesterification/amidation modes - all under mild, environmentally friendly conditions. The ability to avoid environmentally harmful coupling reagents makes the biocatalytic approach both sustainable and scalable. A speciality of enzymes is the ability to synthesise esters and amides in water, which provides an additional advantage for sustainable green chemistry processes. At Enzymicals, we have access to hundreds of these enzymes ready for screening to identify the optimal biocatalyst for your target conversion. Once we've identified the right enzyme, we'll move forward with a seamless transition from screening to synthesis. Want to explore the possibilities of selective ester or amide conversion for your project? Contact us today and let's get started! #EnzymeScreening #Biocatalysis #GreenChemistry #Enzymes #SustainableSynthesis #APIs #CRO #ProcessDevelopment