HB Instruments

Mitochondrial membrane potential (MMP) is a key indicator of mitochondrial health and function, playing a crucial role in energy production and cellular metabolism. Changes in MMP reflect shifts in cellular energy states, making it a vital parameter in research areas such as toxicology, drug discovery, and disease modeling. To support these advanced studies, our latest application note introduces a simple yet powerful method for assessing mitochondrial activity using the automated live-cell imaging system, Celloger® Pro. With its cutting-edge features, researchers can effortlessly monitor MMP changes in real time, providing comprehensive insights into cellular metabolism and intricate processes. To download the application note: https://lnkd.in/gZ-WdQet More information about Celloger®: https://lnkd.in/d5zmFaat #livecellimaging #Celloger #CellogerMiniPlus #CellogerPro #Curiosis #Mitochondria #MMP #CCCP

Congratulations to the team led by Prof. Erkin Seker on their groundbreaking study using a primary cortical cell tri-culture model to explore how amyloid-beta impacts microglial function and triggers neuroinflammatory responses. The team revealed that the combined presence of microglia, neurons, and astrocytes is essential for replicating key changes, such as cytokine profile alterations and microglial motility, in response to amyloid-beta treatment. These findings highlight the critical role of cellular crosstalk in the tri-culture model, revealing how microglia contribute to clearing abnormal proteins and orchestrating inflammatory responses in a more physiologically relevant system.   In this study, the motility and beta-amyloid clearance processes of microglia were monitored in real time using our automated live-cell imaging system, Celloger® Mini Plus. We are proud that Celloger® Mini Plus could contribute to such a significant advancement in neurobiology.   To read the full article: https://lnkd.in/gJ3KYEZ3 More information about Celloger® Mini Plus: https://lnkd.in/g8CTm7hW #livecellimaging #Celloger #CellogerMiniPlus #Curiosis #Microglia #Amyloidbeta #Neurodegeneration

Imagine speeding up your lab tasks with precision, consistency, and less manual labor. Automated liquid handling systems bring a game-changing level of efficiency to the lab. View our informative document below to learn more about how automated liquid handling systems can help improve your workflow, and learn more about our various systems here: https://bit.ly/48WeOru #LabAutomation #LiquidHandling #Gilson #Efficiency #LabLife #ScientificInnovation

Check out our latest application note on NK cell-mediated cytotoxicity, featuring the advanced live-cell imaging capabilities of our Celloger® Pro system. In this application note, we introduce a more accurate, real-time approach using the Celloger® Pro and live-cell staining dyes, offering enhanced intracellular retention and minimizing inaccuracies. This method addresses the limitations of conventional techniques, providing deeper insights into cellular changes and NK cell-mediated cytotoxicity. To download the application note: https://lnkd.in/gZ-WdQet More information about Celloger® Pro: https://lnkd.in/gvu_XANT #livecellimaging #Celloger #CellogerPro #Curiosis #NKcell #Cytotoxicity #Immunotherapy

We are thrilled to announce an exceptional achievement: TWO of our groundbreaking products have been named CES 2025 Innovation Awards Honorees! 🏆 MSP™-320: Redefining digital pathology with next-generation slide scanning technology 🏆 Cellpuri®: Transforming cell separation and concentration for advanced biomedical research This double recognition demonstrates our leadership in cutting-edge biotechnology and digital health innovation. Join us in celebrating this remarkable milestone as we continue to shape the future of healthcare innovation. https://lnkd.in/gF5Ncerg #CES2025 #CESInnovationAwards #DigitalHealth #Winner #Curiosis #Innovation #DigitalPathology #Scanner #MSP #CellSeparation #CellConcentration #Chip #CellPuri

Did you know that cannabis and hemp products are prone to contamination by mycotoxins – toxic compounds from mould – at nearly every stage of production? Despite these risks, US regulations on mycotoxins in cannabis remain inconsistent. Meanwhile, Europe’s push toward legalisation is likely to bring stricter safety mandates. So, how can the industry safeguard consumers and maintain trust? Reliable testing is key! LC-MS technology stands out as the top choice, offering comprehensive mycotoxin screening to protect consumers and uphold brand integrity. Find out more here: https://ow.ly/eMtc50TZp9v. #CannabisIndustry #HempProducts #Mycotoxins #CannabisSafety #QualityControl #LcmsTechnology