iThera Medical

To wrap up our highlights of the top 2024 publications we turn the spotlight to the devices that made this research possible: our preclinical and clinical #MSOT and #RSOM devices – the world’s broadest optoacoustic product portfolio, leading the field of optoacoustic imaging. For more details, please visit our website: https://lnkd.in/dnY-_xhV #optoacoustics #photoacoustics #preclinicalresearch #clinicalreserach

Last but not least, we’re highlighting our clinical Raster-Scanning Optoacoustic Mesoscopy (RSOM) imaging technology in the innovative study, “Non-invasive optoacoustic imaging of dermal microcirculatory revascularization in diet-induced obese mice undergoing exercise intervention”. In this study Vasilis Ntziachristos and the research team MunichImaging used RSOM in combination with our Multi-Spectral Optoacoustic Tomography (MSOT) imaging technology to precisely visualize the microvasculature of dermal white adipose tissue (dWAT) and quantify key structural parameters, such as skin layer thickness and vascular density. These findings demonstrate the potential of #RSOM to non-invasively monitor microcirculatory dysfunction and intervention responses in metabolic diseases. For more details and access to the publication, follow this link: https://lnkd.in/dWv3AEAi #optoacoustics #photoacoustics #clinicalresearch

We’re thrilled to announce the official kick-off of project miniOPUS, funded by the Bayerische Verbundforschungsprogramm (BayVFP)! This collaborative effort brings together iThera Medical, MunichImaging, and Fraunhofer EMFT, with strategic support from Fraunhofer ENAS. miniOPUS is set to revolutionize optoacoustic imaging by developing next-generation hardware, software, and algorithms. Our key focus areas are: ✅ System miniaturization using VCSEL and xMUT technology for enhanced portability ✅ Cost reduction by a factor of 100 ✅ Laser Class 1 operation for safer and more accessible technology ✅ Reduced computational overhead for real-time imaging ✅ Synergistic optoacoustic & ultrasound data analysis, minimizing artefacts and improving image quality We’re excited to push the boundaries of photoacoustic medical imaging! #optoacoustics #photoacoustics 

Congratulations to Ferdinand Knieling and his team at Universitätsklinikum Erlangen to being awarded the Felix-Jerusalem-Preis by the Deutsche Gesellschaft für Muskelkranke e.V. for their work on #MSOT optoacoustic muscle imaging in children with neuromuscular diseases. We look forward to continuing our important collaboration!

Established imaging tools leave diagnostic gaps in breast cancer diagnosis and assessment. However, recent studies indicate that multispectral optoacoustic tomography (MSOT) could improve diagnostic accuracy in clinical routine. In our latest blog, ‘Exploring MSOT to detect and characterize human breast cancer’ our Chief Medical Officer Dr. Petra Siebenhandl-Wolff, PhD explores research conducted at the University of Cambridge and MunichImaging where the researchers propose that #MSOT demonstrated the ability to rule out cancer and reduce unnecessary biopsies, related complications, and patient anxiety. Read the full blog to discover how MSOT could bride critical diagnostic gaps left by the clinical gold standards. https://lnkd.in/dzhUu7hK #optoacoustics #photoacoustics #clinicalresearch #breastcancer #mammography #breastimaging

We continue highlighting 2024 publications with more ground-breaking research conducted using our preclinical Raster-Scanning Optoacoustic Mesocopy (#RSOM) imaging technology. Researchers at FAU Erlangen-Nürnberg are driving innovation in inflammatory bowel disease (IBD) in their study, ‘In Vivo Assessment of Deep Vascular Patterns in Murine Colitis Using Optoacoustic Mesocopic Imaging.’ In this study, Adrian Bühler and the team at FAU demonstrated the potential of Transrectal Absorber-Guided RSOM (TAG-RSOM) to image deep vascular networks in the colon wall in murine models of colitis. This cutting-edge imaging technology enables researchers to visualize and analyze vascular networks in vivo with extraordinary precision. For more details and access to the publication, follow this link: https://lnkd.in/dtqtbmbt #optoacoustics #photoacoustics #preclinicalresearch

This week we continue highlighting 2024 publications by focusing on research conducted using our clinical Multispectral Optoacoustic Tomography (MSOT) technology. Our team has selected research conducted at the Universitätsklinikum Erlangen for their pilot study paving the way for better diagnostics, “Non-invasive optoacoustic imaging of glycogen-storage and muscle degeneration in late-onset Pompe disease.” In this study, Ferdinand Knieling's research team advance our understanding of Pompe disease while highlighting the potential of #MSOT in clinical diagnostics and tracking of disease progression for neuromuscular disorders. For more details and access to the publication, follow this link: https://lnkd.in/dm_U6mdK #optoacoustics #photoacoustics #clinicalresearch

To begin highlighting 2024 publications we focus on research conducted using our preclinical Multispectral Optoacoustic Tomography (MSOT) technology. With a total of 64 preclinical #MSOT publications selecting one publication was not an easy task. Our team selected the following publication to highlight: “Homo-Dyad with Outer Hydration Layer Approach for Developing NIR-II Chromophore of High Stability and Water-Solubility as Injectable and Sprayable Optical Probe” In this study, the researchers at South China University of Technology (SCUT) focus on developing a novel NIR-II chromophore with enhanced stability and water solubility, integrating such chromophores with MSOT’s optoacoustic imaging capabilities could be a promising direction for future research in non-invasive deep-tissue imaging. For more details and access to the publication, follow this link:  https://lnkd.in/dPxKbeZi #optoacoustics #photoacoustics #preclinicalresearch  

Last week, we had the pleasure of attending and participating in Photonics West 2025 in San Francisco! The event was packed with insightful discussions and meaningful connections that will help shape the future of optoacoustic imaging. The highlight of the conference? Showcasing our VCSEL-based probe prototype (VCSEL = vertical-cavity surface-emitting lasers). We expect the innovative VCSEL subsystem light source to be the missing puzzle piece for translating optoacoustic imaging into routine clinical use by replacing traditional costly and large solid state laser systems. iThera’s initial application focus lays on assessing soft tissue perfusion and oxygenation. Our CTO, Dr. Patrick Leisching explains, “These game-changing improvements will facilitate the translation of our technology from research into routine diagnostic use and also enable future sensing applications, making optoacoustic technology widely accessible across different care settings.” Swipe through to catch a glimpse of our team's activities during the conference! #optoacoustics #photoacoustics #VSCEL #PhotonicsWest2025

Congratulations to Steven Thng and his team at Skin Research Institute of Singapore (SRIS) for successfully demonstrating the value of our #MSOT imaging technology to map out the extent of basal cell carcinoma to more effectively and efficiently perform Moh's surgery. #photoacoustics #optoacoustics #clinicalresearch