The brightness temperature of the Geostationary Meteorological Satellite (GSM)-5 water vapor channel (Tb_6.7) and relative humidity, precipitable water, specific humidity and temperature observed by radionsondes over the Tibetan Plateau are compared for the summer of 1995. A wavelength of 6.7 μm was employed, so most of the radiation sensed by the satellite comes from the atmospheric layer between 300 and 600 hPa. The plateau altitude is 3, 000 to 4, 000 m, and GMS-5 Tb_6.7 over the Plateau represents the moisture information above that. The regression equations of upper tropospheric humidity (UTH) and precipitable water with Tb_6.7 are presented in this paper. The relationships between Tb_6.7 and observed temperature and specific humidity at the standard pressure levels are then compared to each other. Results show that, over the Plateau, Tb_6.7 is sensitive to the moisture information around 200 to 300 hPa height. The results demonstrate that Tb_6.7 is useful for not only qualitatively analyzing the moisture transporting field over and around the Tibetan Plateau, but also quantitatively inferring UTH and precipitable water above 400 hPa (W₄₀₀). Estimates of W₄₀₀ for July and August 1995 and its diurnal variability over and around the Tibetan Plateau are presented.