Discngine

As we wrap up 2024, take a look back at our top 3 most engaging content pieces and events of the year! 💻Product Spotlight: How Bayer Crop scientists streamline their lab screening activities using Discngine Assay: https://bit.ly/3ONAb53 ⭐ Event Spotlight: Discngine turns 20! https://bit.ly/3OUFeAB 📖 Study Spotlight: How accurate are AF3 predicted protein-protein complexes? A PD-1 case study: https://bit.ly/3BmsMXi Stay tuned for more content highlights throughout December! ⭐ #discngine #labinformatics #bioinformatics #drugdiscovery #20years

💊 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗼𝗳 𝘁𝗵𝗲 𝗠𝗼𝗻𝘁𝗵 𝗼𝗻 𝗔𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰 𝗗𝗿𝘂𝗴 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 – 𝗜𝗻𝘀𝗽𝗶𝗿𝗲𝗱 𝗯𝘆 𝗣𝗦𝗗𝗜 𝘁𝗮𝗹𝗸 The Roche drug discovery team is fighting antibacterial resistance by targeting the lipopolysaccharide transporter #Lpt in Gram-negative bacteria with novel compounds. The recently resolved high-resolution #CryoEM structure of the Lpt complex provides valuable insights into the binding mechanism of these new compounds, laying the foundation for designing novel, effective antibiotics. Thank you, Thomas Clairfeuille, for sharing structural study and progress on this important project. 👉 Check out how structural insights greatly contributed to the antibody discovery here: https://lnkd.in/e6A76Rd4 #discngine #3decision #antibody #drugdiscovery #antibodyresistance

𝗪𝗵𝗮𝘁 𝗶𝘀 𝘁𝗵𝗲 𝘀𝘁𝗮𝘁𝗲 𝗼𝗳 𝗔𝗜/𝗠𝗟 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝗶𝗲𝘀 𝗶𝗻 𝘀𝘂𝗽𝗽𝗼𝗿𝘁𝗶𝗻𝗴 𝗮𝗻𝘁𝗶𝗯𝗼𝗱𝘆 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗮𝗯𝗶𝗹𝗶𝘁𝘆?💡 Following the interesting panel discussion at the Discngine Meetup, we’ve summarized expert insights from both pharma and academia in a blog post. Discover the current status and impact of new technologies supporting antibody developability, as well as future trends in the field: https://bit.ly/4hRnKT3 Anything you would like to add? Write us in the comments! 👇 #discngine #antibody #discovery #developability #assessment #ai

Discngine @ ELRIGfr conference - starts tomorrow! Our Discngine Assay team is joining the ELRIG France conference in the next 2 days. We’re excited to reunite with colleagues in the field, gain new insights in robotics and lab informatics, and make new collaborations in a very pleasant atmosphere. 📆 20 - 21 November 2024 📌 Servier Research and Development Institute in Paris-Saclay 🔗https://bit.ly/4hVvcNe Ana Marqués Altava Fabrice Casagrande Thomas Blarre Pierrick Chabot Don't miss the chance to meet us at the conference!🤝 #Discngine #LabInformatics #DiscngineAssay #ELRIGfr

#PSDI2024 - it's a wrap!💪 Yesterday was the final day of PSDI, and it was just as engaging as the previous ones. There were presentations on emerging technologies in the field and insightful SBDD case studies from industry and academia. Being a sponsor of PSDI meetings is always a privilege. We’re grateful for the opportunity to connect with such an inspiring community of structural biologists in a very pleasant and familiar setting. We extend a warm thank you to the organizers, all the speakers and sponsors, and everyone who stopped by our booth and poster. Elisa Martino Lorena Zara Gabriella Jonasson, Ph.D. Marija Martini Catch a glimpse of the atmosphere in our video! 👇 See you next year in Basel! #discngine #3decision #PSDI #structuralbiology #cryoEM #alphafold

Great time at PSDI in Paris today! 🌟 We appreciate presentations and engaging insights about: ✔️ innovative ways of producing challenging targets such as membrane proteins ✔️ advancements in structural biophysics and NMR ✔️ case studies of AI and experimental structural data synergies 💬As Dave G Brown mentioned, every target is challenging. Just as we believe we are gaining a deeper understanding of them, new challenges arise. 💡One of Matthias Haffke, PhD recommendations is to let AI guide the generation of hypotheses and ideas. Many thanks to those visiting our booth 1️⃣1️⃣ and poster 6️⃣. For those who haven’t yet stopped by, you have one more day to meet our team. Gabriella Jonasson, Ph.D. Lorena Zara Elisa Martino Marija Martini 🗒️Check the program for tomorrow here: https://lnkd.in/eaGE6rSD Looking forward to meeting you! 👋

We’re ready and excited for PSDI2024🎉 Gabriella Jonasson, Ph.D. Lorena Zara Elisa Martino Marija Martini are looking forward to meeting you at our booth #11 over the next three days. Join us to see our poster: "How Accurate Are AF3-Predicted Complexes?" Discover insights on AlphaFold3's predictions for PD-1/antibody complexes, including accuracy, the role of post-translational modifications, and AI limitations.

Join #Discngine at PEGS Europe 2024, with Peter Schmidtke attending to discuss advancements in biotherapeutics, protein and antibody engineering, and emerging research in the field. Connect with Peter for insightful conversations on enhancing research initiatives through Discngine’s innovative software solutions. For more information check their website: https://bit.ly/48EUYkv #PEGS #biotherapeutics #proteinengineering

PSDI is just around the corner and we're ready to participate! 🌟 Join us to engage in interesting discussions around science and technology for protein structure determination. Visit us at booth 1️⃣1️⃣ and check out our scientific poster on the accuracy of AF3 predicted models! Discover: https://bit.ly/3BINBvR #discngine #3decision #psdi #structural biology #proteinstructure #drugdiscovery

𝗔𝘁𝘁𝗲𝗻𝗱𝗶𝗻𝗴 𝗣𝗦𝗗𝗜 𝟮𝟬𝟮𝟰 https://bit.ly/3YeqkcG❓ This year again, our scientific team has prepared an engaging content to support discussions and networking. The event takes place in 𝘏𝘰𝘵𝘦𝘭 𝘕𝘰𝘷𝘰𝘵𝘦𝘭 𝘗𝘢𝘳𝘪𝘴 𝘤𝘦𝘯𝘵𝘳𝘦 𝘛𝘰𝘶𝘳 𝘌𝘪𝘧𝘧𝘦𝘭 from Nov 10-12! Join us in person at our Booth #11 to discover: ✨ Live demo of 3decision's latest features 🤖 AI model & experimental data integration science 📣 Exclusive announcements just for attendees 📊 Scientific poster on AlphaFold3 models accuracy …and so much more! Don't miss out! https://bit.ly/48kvadd Elisa Martino Lorena Zara Gabriella Jonasson, Ph.D. Marija Martini #3decision #discngine #psdi #event #structuralbiology #drugdiscovery