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Center-Within-Trial Versus Trial-Level Evaluation of ...
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由 LA Renfro 著作2014被引用 16 次 — Evaluation of candidate surrogate endpoints using individual patient data from multiple clinical trials is considered the gold standard approach to validate ...
Center-within-trial versus trial-level evaluation of surrogate ...
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由 LA Renfro 著作2014被引用 16 次 — A surrogate endpoint is considered to be validated for use in future clinical trials of the same disease setting when both strong patient-level surrogacy and ...
Center-within-trial versus trial-level evaluation of surrogate ...
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A specific grouping approach is derived to successfully apply surrogate endpoint evaluation on data from a single trial, which may allow for the ...
Center-within-trial versus trial-level evaluation of surrogate ...
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Dive into the research topics of 'Center-within-trial versus trial-level evaluation of surrogate endpoints'. Together they form a unique fingerprint. Sort by ...
Center-within-trial versus trial-level evaluation of surrogate ...
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Evaluation of candidate surrogate endpoints using individual patient data from multiple clinical trials is considered the gold standard approach to validate ...
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Surrogate endpoint evaluation using data from one large ...
National Institutes of Health (NIH) (.gov)
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由 M Geybels 著作2021被引用 1 次 — The meta-analysis-based surrogate endpoint evaluation (SEE) integrates data from multiple, usually smaller, trials to statistically confirm a surrogate endpoint ...
The meta-analytic framework for the evaluation of ...
ResearchGate
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2024年10月22日 — Center-Within-Trial Versus Trial-Level Evaluation of Surrogate Endpoints ... surrogate and the clinical endpoint, called the trial-level ...
Frequently asked questions on surrogate endpoints in ...
The Lancet
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The Lancet
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由 A Mittal 著作被引用 1 次 — In this article, we provide a comprehensive review of surrogate endpoints currently used in oncology trials both in curative and advanced disease settings.
assessing pathologic complete response as a trial-level ...
Annals of Oncology
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Annals of Oncology
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由 EL Korn 著作2016被引用 57 次 — A trial-level surrogate end point for a randomized clinical trial may allow assessment of the relative benefits of the treatment to be performed at an ...
Handling missing within‐study correlations in the ...
Wiley Online Library
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Wiley Online Library
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2023年9月3日 — Rigorous evaluation of surrogate endpoints is performed in a trial-level analysis in which the strength of the association between treatment ...
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