Abstract The excessive release of reactive oxygen species (ROS) can result in the development of chronic inflammation. The mechanisms involved in inflammation are various, with endoplasmic reticulum (ER) stress known to be among them. We have previously shown that black ginseng (BG) reduced lipid accumulation in and enhanced the antioxidant function of the liver in vitro and in vivo mostly due to ginsenoside Rb1, Rg3 and Rk1 components. https://lnkd.in/g2zNhCY5
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Ginseng is beneficial for anti-aging due to its active components, such as saponins, polysaccharides, and active peptides. These components exhibit antioxidant properties, enhance DNA repair, and have neuroprotective effects, contributing to the reduction of DNA damage and delaying the aging process. Ginseng's active components orchestrate mechanisms to slow ageing through enhanced antioxidant enzyme expression and DNA repair, a new review has concluded. The authors from Japan and China have summarised that the active components of ginseng, including saponins, polysaccharides, and active peptides, have antioxidant, anti-apoptotic, neuroprotective, and age-delaying effects. They note that while DNA damage is the main factor associated with ageing, the mechanism through which the active ingredients of ginseng reduce DNA damage and delay ageing has not been comprehensively described previously. https://lnkd.in/gNJT4RzY
Ginseng: the root to antioxidant and DNA repair
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