Department of Biotechnology

Welcome to the Official Instagram Page of the Department of Biotechnology! 🌿🔬 Your go-to destination for updates on cutting-edge research, innovations, & initiatives shaping the future of biotechnology. Visit our page: https://lnkd.in/gWb3JQAu Rajesh Gokhale BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD) BRIC-NCCS Pune BRIC-National Institute of Biomedical Genomics BRIC-National Institute of Immunology BRIC-RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY BRIC-National Institute of Animal Biotechnology (NIAB) BRIC NABI Institute for Stem Cell Science and Regenerative Medicine (BRIC-inStem) Institute of Life Sciences National Institute of Plant Genome Research - NIPGR Translational Health Science and Technology Institute (THSTI) National Brain Research Centre

A glimpse into history in the making! The #GenomeINDIA project is a key to India's biotech revolution, marking a major milestone in our research journey. It will give new momentum to India's efforts and infuse our #biotech ambitions with fresh energy. Together, we're building a brighter future. #Genomics #Research Rajesh Gokhale| Office of the Principal Scientific Adviser to the Government of India | CSIR India | Indian Council of Medical Research (ICMR)| India DST| Centre for Cellular and Molecular Biology| ICGEB| CSIR-IGIB| AIIMS (All India Institute of Medical Sciences, New Delhi)| Indian Institute of Science (IISc)| Regional Centre for Biotechnology| Indian Biological Data Centre, Regional Centre for Biotechnology, Faridabad| BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD)| Institute of Bioresources and Sustainable Development (IBSD)| Institute of Life Sciences| Institute for Stem Cell Science and Regenerative Medicine (BRIC-inStem)| National Brain Research Centre BRIC-NCCS Pune BRIC-National Institute of Animal Biotechnology (NIAB) BRIC - National Institute of Plant Genome Research - NIPGR RGCB - Rajiv Gandhi Centre for Biotechnology| Translational Health Science and Technology Institute (THSTI)

Prof. Bhabatosh Das' lab at BRIC-Translational Health Science and Technology Institute (THSTI) has sequenced the whole genome of Megasphaera elsdenii, isolated from the stool sample of a healthy Indian subject. This genomic analysis provides valuable insights into M. elsdenii's ability to ferment various carbohydrates and organic acids, producing short-chain #fattyacids. M. elsdenii is crucial in maintaining microbial balance within the gut, regulating pH, and modulating #immune responses. Understanding the #genomic features of M. elsdenii will aid in developing synbiotics to improve gut health. #ODOG #Immunity Rajesh Gokhale Office of the Principal Scientific Adviser to the Government of India CSIR India Indian Council of Medical Research (ICMR) India DST BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD) Institute of Bioresources and Sustainable Development (IBSD) Institute of Life Sciences Institute for Stem Cell Science and Regenerative Medicine (BRIC-inStem) National Agri-Food Biotechnology Institute (NABI) National Brain Research Centre BRIC-NCCS Pune BRIC-National Institute of Animal Biotechnology (NIAB) BRIC-National Institute of Biomedical Genomics BRIC-National Institute of Immunology BRIC - National Institute of Plant Genome Research - NIPGR RGCB - Rajiv Gandhi Centre for Biotechnology Regional Centre for Biotechnology

#OneDayOneGenome Cholera, caused by Vibrio cholerae, spreads through contaminated food/water and can lead to severe dehydration and death if untreated. Prof. Bhabatosh Das' lab at BRIC-Translational Health Science and Technology Institute (THSTI) sequenced V. cholerae strain IDH08148 from a patient, providing insights into its evolving genome and implications for disease severity and management. #Cholera #VibrioCholerae #Genomics #PublicHealth Accession numbers: GCA_004309765.1 (NCBI) INGCA000000190 (hashtag #IBDC) Indian Biological Data Centre, Regional Centre for Biotechnology, Faridabad Rajesh Gokhale Office of the Principal Scientific Adviser to the Government of India Indian Council of Medical Research (ICMR) CSIR India MyGov India BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD) Institute of Bioresources and Sustainable Development (IBSD) Institute of Life Sciences Institute for Stem Cell Science and Regenerative Medicine (BRIC-inStem) National Brain Research Centre BRIC-NCCS Pune BRIC-National Institute of Animal Biotechnology (NIAB) BRIC-National Institute of Biomedical Genomics BRIC-National Institute of Immunology RGCB - Rajiv Gandhi Centre for Biotechnology Regional Centre for Biotechnology

"Fighting Pests with RNAi: A New Hope for Maize Farmers" Fall Armyworm is a devastating insect pest for maize and many other crops, causing huge losses for #farmers in India and worldwide. Traditional pest control methods rely heavily on chemical pesticides, which harm the environment and human health, and often lose effectiveness as pests develop resistance. This study by Vadassery lab at BRIC - National Institute of Plant Genome Research - NIPGR in collaboration with ICAR- Indian Council of Agricultural Research-IIMR, Ludhiana, uses a promising new solution: RNA interference (RNAi), a method that targets specific genes in insect pests, making them unable to grow or reproduce properly. #Researchers focused on three important genes in the Fall Armyworm—responsible for vital processes like protein transport and detoxifying harmful substances. When these genes were "silenced" using #RNAi, the pests showed slower growth, higher death rates, and fewer offspring. Some even started cannibalizing each other! The scientists also tested this approach by external application of RNAi constructs to #maize leaves. The results showed, pests ate less, grew poorly, and showed unusual behaviors, making this method a potential game-changer for pest control. This eco-friendly strategy could reduce pesticide use and offer farmers a sustainable way to save their crops. With further research, RNAi-based pesticides and pest control might soon become a solution for #farming challenges and a part of Integrated Pest Management (IPM). Rajesh Gokhale

🚨 Deadline Extended till January 25! Join CCAMP Tech Showcase 5.0 and explore cutting-edge innovations across the Diagnostics, Therapeutics, and Medical Devices sectors. ✅Connect directly with inventors ✅Discover solutions relevant to your organisation's objective. ✅Kickstart collaborations or in-license technologies that fit your strategic interests. 🗓️When? 21 February 📍Where? CCAMP 🔗 Register now: Inventor: https://lnkd.in/g62SSEf9 Industry: https://lnkd.in/gaqCiqPz More details: https://lnkd.in/gnKHgBJf 📧 Contact: aaditilele@ccamp.res.in, chetanchandola@ccamp.res.in 📞 Call us: 08067185322 Taslimarif Saiyed, PhD Biotechnology Industry Research Assistance Council (BIRAC) IT BT Department, Karnataka Startup Karnataka K-tech Biotechnology Facilitation Cell Karnataka Innovation and Technology Society Atal Innovation Mission Official Department of Science & Technology, Government of India MeitY Startup Hub

Latest news published in TheHindu highlights key research on rethinking the age-old notion whether #irondeficiency causes #anaemia 🔗Click here to read: https://lnkd.in/gx9fWxzY Rajesh Gokhale Department of Biotechnology Indian Council of Medical Research (ICMR) ICMR-National Institute of Nutrition St John’s Medical College, Bengaluru, India Banaras Hindu University Centre for Cellular and Molecular Biology

A Rising Star in the World of Probiotics: Faecalibacterium prausnitzii Indica Prof. Bhabatosh’s group at BRIC-Translational Health Science and Technology Institute (THSTI) decoded the complete genome of Faecalibacterium prausnitzii from a healthy Indian adult, shedding light on carbohydrate breakdown, gut immunity, and metabolism to aid in managing inflammatory bowel disease and undernutrition. #Guthealth #ODOG Rajesh Gokhale Office of the Principal Scientific Adviser to the Government of India CSIR India Indian Council of Medical Research (ICMR) MyGov India BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD) Institute of Bioresources and Sustainable Development (IBSD) Institute of Life Sciences Institute for Stem Cell Science and Regenerative Medicine (BRIC-inStem) National Brain Research Centre BRIC-NCCS Pune BRIC-National Institute of Animal Biotechnology (NIAB) BRIC-National Institute of Immunology BRIC - National Institute of Plant Genome Research - NIPGR RGCB - Rajiv Gandhi Centre for Biotechnology Regional Centre for Biotechnology

Research from Dr Praveen Kumar Vemula Lab translated into pesticide-neutralizing suits for protection of farmers - Kisan Kavach - launched in December 2024. The news is covered in Krishak Jagat, a national newspaper for agriculturists. We are proud to bring the benefits of science and research to our annadaataa, our farmers. 🙏 https://lnkd.in/gVMBdugH Department of Biotechnology Department of Science and Technology Rajesh Gokhale

Human Microbiome Research facility of BRIC-National Institute of Biomedical Genomics,isolated Klebsiella pneumonia NIBMG_HMR_27 from chronic diabetic foot ulcer. This bacterium is known for producing thick polysaccharide capsules that shield it from immune defenses and its remarkable ability to resist antibiotics.  These molecular adaptations make K. pneumoniae a resilient and virulent pathogen, posing significant challenges in wound care and infection management. Genome sequencing will aid in early diagnosis and the development of effective treatment regimens for chronic wound healing. For more information https://lnkd.in/gvidvfXn #SkinMicrobiome #Genomics #AntibioticResistance Rajesh Gokhale CSIR India Indian Council of Medical Research (ICMR) Office of the Principal Scientific Adviser to the Government of India India DST BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD) Institute of Bioresources and Sustainable Development (IBSD) Institute of Life Sciences Institute for Stem Cell Science and Regenerative Medicine (BRIC-inStem) National Brain Research Centre BRIC-NCCS Pune BRIC-National Institute of Animal Biotechnology (NIAB) BRIC-National Institute of Immunology BRIC - National Institute of Plant Genome Research - NIPGR RGCB - Rajiv Gandhi Centre for Biotechnology Translational Health Science and Technology Institute (THSTI)