No abstract available

[en] The appearance of side effects was monitored in 70 selected patients who underwent radiculography and myelography. After the examination, a rapid return to normal activity was recommended. In accordance with literature no greater incidence of side effects was found in patients who were allowed to get up soon after myelography or radiculography, than in patients confined to bed for some hours. These results are essentially attributable to the low toxicity of the contrast medium used in this study (Iopamidol), and to an adeguate hydratation of the patients after examination

[en] It is important to increase the iodine delivery rate (I), that is the iodine concentration of the contrast material (C) x the flow rate of the contrast material (Q), through microcatheters to obtain arteriograms of the highest contrast. It is known that C is an important factor that influences I. The purpose of this study is to establish a method of hydrodynamic calculation of the optimum iodine concentration (i.e., the iodine concentration at which I becomes maximum) of the contrast material and its flow rate through commercially available microcatheters. Iopamidol, ioversol and iohexol of ten iodine concentrations were used. Iodine delivery rates (I meas) of each contrast material through ten microcatheters were measured. The calculated iodine delivery rate (I cal) and calculated optimum iodine concentration (calculated C opt) were obtained with spreadsheet software. The agreement between I cal and I meas was studied by correlation and logarithmic Bland-Altman analyses. The value of the calculated C opt was within the optimum range of iodine concentrations (i.e. the range of iodine concentrations at which I meas becomes 90% or more of the maximum) in all cases. A good correlation between I cal and I meas (I cal = 1.08 I meas, r = 0.99) was observed. Logarithmic Bland-Altman analysis showed that the 95% confidence interval of I cal/I meas was between 0.82 and 1.29. In conclusion, hydrodynamic calculation with spreadsheet software is an accurate, generally applicable and cost-saving method to estimate the value of the optimum iodine concentration and its flow rate through microcatheters

[en] The experience is reported which was gained in 1974 with a central reporting, registration and data processing system for radiation doses received by workers in nearly all of the national nuclear power plants. The number of people controlled by the National Film Dosimetric Service mounted to 11,490. Also, the development of an automated thermoluminescence dosimetry system made good progress, especially the output equipment which underwent improvement. This system has the possibility of replacing film dosimetry in the future at the National Service. In the meantime, the system found some interesting applications, among which is testing the admissability of radiological caries control in large groups of the population by measuring the local dose received orally. Whole-body counting was used for contamination control of personnel in nuclear power plants, for which purpose a Ge(Li) detector was introduced. A study was begun on the use of ⁴⁰K as a tracer in the determination of the ratio of lean versus fat body mass in man

[en] Iohexol was administered orally in five dogs. The dose, gastrointestinal (GI) transit time, appearance of mucosal patterns and side effects were studied. Three different doses (525, 700, 875 mgI/kg) were used in each dog at 1-week intervals. GI transit time was rapid. In each dose, gastric emptying commenced immediately after administration of the contrast medium, and was completed within 30–60 min with doses of 525–700 mgI/kg and 90–120 min with 875 mgI/kg. Large intestinal filling was observed within 60-90 min. In the majority of studies, the mucosal border appeared as a thin homogeneous halo of lucency surrounding the more opaque bowel lumen contents. The contrast intensity was not adequate with the lowest dose. The image quality did not deteriorate along the GI tract. No adverse reactions were found. Iohexol is an alternative GI contrast medium in the dog when contrast media are contraindicated

No abstract available

[en] Urography was performed in 20 patients using the new non-ionic contrast medium iohexol (Omnipaque) and in 22 patients using the conventional ionic medium metrizoate (Isopaque) in a randomized, double blind comparison. Iohexol caused significantly less subjective reactions and less tachycardia than metrizoate. No significant difference between the contrast media was observed regarding the influence on blood pressure, hematologic parameters, or clinical chemical parameters in blood and urine. Urographic films of similar and high quality were obtained with both contrast media. (Auth.)

[en] The image contrast of X-ray CT systems depends on the properties of the imaging system, the number of grey scales used in the digital sampling process, and the addition or otherwise of a contrast medium. The effect of contrast medium is often emphasized in the peripheral rim of pathologic masses. In this study, a special hexagonal test object made of acrylic phosphate and a cylindrical container were employed. When the contrast medium IOPAMIRON 300 was used to fill the space between the test object and its cylindrical container, a contrast-enhanced peripheral rim with or without signal of defect was observed. Visual perceptibility was examined from the signals resulting from varying contrast by use of contrast medium and adjusting the grey scale by image processing. Threshold contrast influenced by window width was recorded in each instance using statistical analyses. While window width was inversely proportional to image contrast, different ranges of window width and image contrast provided better visual perceptibility for each concentration of the contrast medium. The range of window width for obtaining the best visual perceptibility was determined for a contrast-enhanced image. (author)

No abstract available

[en] To compare the clinical efficacy of Prmiary (iopamidol) as an intravenous nonionic contrast material in abdominal CT with that of Ultravist (iopromide), an established nonionic contrast agent. Thirty patients who had undergone abdominal CT using Ultravist during the previous two-year period underwent abdominal CT using Prmiary after written consent to its use had been obtained. During scanning using both of these media, the regions of interest facility was used to measure, in Hounsfield units, attenvation in the liver, bilateral kidneys, aorta, portal vein, and inferior vena cava, and the paired t test was used to assess the statistical significance of the findings. The severity of adverse effects, if any, experienced during contrast material injection was classified as mild or severe, and their frequency was examined. There was no significant difference between Pamiray and Ultravist in terms of the degree of contrast enhancement observed (p>0.05). During scanning in which Pamiray was used, three patients felt hot and two experienced mild nausea, but in none were adverse effects severe. For abdominal CT, Pamiray is comparable to Ultravist in terms of contrast enhancement. Where the use of a nonionic contrast medium is required, Pamiray could thus be a useful clinical alternative