No abstract available

No abstract available

[en] Highlights: • HAIC shows great effecacy in the treatment of unresectable hepatocellular carcinoma. • The nomogram accurately predicts the survival of patients after HAIC. • Our prognostic model is superior to the conventional staging systems. Hepatic arterial infusion chemotherapy (HAIC) has shown encouraging efficacy in the treatment of hepatocellular carcinoma (HCC). This study aims to establish and validate a novel nomogram to predict individualized survival outcomes for patients with unresectable HCC after HAIC.

[en] To determine the risk factors and patterns of recurrence after radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) meeting the up-to-seven criteria and to develop a nomogram to predict the recurrence free survival (RFS).

No abstract available

[en] To retrospectively test 2 nomograms recently validated as prognostic tools for patients with oropharyngeal cancer treated with curative radiation-based therapy, in 184 consecutive subjects treated from April 2004 to January 2016.

No abstract available

[en] Highlights: • Methylation-induced SPG20 silence facilitates gastric carcinogenesis. • SPG20 silencing induces cell proliferation by activating EGFR/MAPK signaling pathway. • The nomogram based on spartin provided survival prediction of gastric cancer. Spastic paraplegia 20 methylation was characterized in gastric cancer in our previous study. However, its mechanism remains unknown. Cell proliferation, colony formation, flow cytometry, wound healing, in vitro Transwell assays and in vivo xenografts were performed. A nomogram model was established to make a more accurate prognostic prediction for gastric cancer patients. Knockout of Spastic paraplegia 20 promoted gastric cancer cell proliferation, G2/M arrest in vitro and tumor growth in vivo. The EGFR/MAPK pathway was activated as a consequence of Spastic paraplegia 20 deletion. EGFR kinase or ERK1/2 inhibitors impaired Spastic paraplegia 20 knockout-induced cancer cell growth. Gastric cancer patients with poor spartin expression (72/161, 44.7%) exhibited a worse prognosis compared with the high expression group with median survival times of 16 and 54 months, respectively. The nomogram model stratified gastric cancer patients into 3 distinct prognostic groups with 3-year survival rates of 100%, 77%, and 35%. Furthermore, it had a better discrimination than the TNM staging system (C index: 0.785, AIC: 752.8708 VS. C index: 0.712; AIC: 775.1223). Methylation-induced Spastic paraplegia 20 silencing facilitates gastric cancer cell proliferation by activating the EGFR/MAPK signaling pathway. The nomogram based on spartin expression provided significantly better discrimination compared with the traditional AJCC TNM staging system and provided an individualized prediction of the survival for gastric cancer patient survival.

[en] In methodical recommendations described are the problems of the technique for investigations, measurement metrology and estimation of the diagram material quality while neutron logging using serial equipment. Much attention is given to the methods of individual interpretation of neutron logging data and to the processing of the results obtained by ''hand interpretation''. The set of pallets for the main serial equipment of the commersial use is given

[en] Highlights: • Quantitative 3D radiomics features are extracted and analyzed. • A radiomics nomogram was developed for differentiating MIA and IAC groups in patients with sub-solid pulmonary nodules. • The proposed nomogram yields 0.943 AUC and 0.912 AUC in the training set and validation set, respectively. -- Abstract: To evaluate the preoperative differentiation between the minimally invasive adenocarcinoma (MIA) and invasive adenocarcinoma (IAC) in patients with sub-solid pulmonary nodules using a radiomics nomogram.