[en] Short communication

[en] In this paper, we investigated three ligand systems, symmetric and asymmetric pyridyl-containing tridentate ligands (L¹NH₂ (bis(2-pyridylmethyl)-amino)-ethylamine, L²H (bis(2-pyridylmethyl)-amino)-acetic acid, L³NH₂ [(6-amino-hexyl)-pyridyl-2-methyl-amino]- acetic acid) as bifunctional chelating agents for labeling biomolecules. These ligands reacted with the precursor fac-[¹⁸⁸Re(CO)₃(H₂O)₃]⁺ and yielded the radioactive complexes fac-[¹⁸⁸Re(CO)₃L] (L = three ligands), which were identified by RP-HPLC. The corresponding stable rhenium tricarbonyl complexes (1-3) were allowed for macroscopic identification of the radiochemical compounds. ¹⁸⁸Re tricarbonyl complexes, with log P_o/w values ranging from -1.36 to -0.32, were obtained with yields of ≥90% using ligand concentrations within the 10^-6-10^-4M range. Challenge studies with cysteine and histidine revealed the high stability properties of these radioactive complexes, and biodistribution studies in normal mice indicated a fast rate of blood clearance and high rate of total radioactivity excretion, primarily through the renal-urinary pathway. In summary, these asymmetric and symmetric pyridyl-containing tridentate ligands are potent bifunctional chelators for the future biomolecules labeling of fac- [¹⁸⁸Re(CO)₃(H₂O)₃]⁺. (author)

[en] Optimum methods of synthesis rhenium(V) complexes with 3-ethyl-4-methyl-1,2,4-threeazoltiol-5 were worked out. It is proved that this ligand to rhenium coordinates by means of atom sulfur group of tiony. Determined that the medium in which the synthesis is carried out, influence on torming composition complexes

[en] Short communication

No abstract available

[en] Data on the synthesis of previously unknown semicoordination compounds of Re(3) by means of π-C₅H₅ Re(CO)₃ and π-C₅H₅ Re(CO)₂ PPh₃ oxidation by chlorine, thionyl chloride, iodine are presented. Chlorination has been carried out in the range of -15-+29 deg in the CH₂Cl₂, CCl₄ media. Iodination of π-C₅₅ Re( O)₃ is performed in DMCO at 20 deg. Chemical properties, structure, isomery of the compounds obtained are studied

No abstract available

[en] The compounds Re(CO)₃Cl(L)₂, L = triphenylphosphine, tri-p-tolyphosphine, and Re(CO)₃-Cl(L'), L'=1,2-bis(diethylphosphinoethane) are luminescent in solution and in crystalline form when excited between 351 nm and 514 nm at temperatures ranging from 10 K to room temperature. The absorption spectra contain a weak (E ∼ 10 M^-1 cm^-1) band in the visible region of the spectrum between 400 and 500 nm. The lowest energy transition giving rise to these spectroscopic features is assigned to a d-d transition

No abstract available

[en] The purpose of the present work is development of optimal syntheses conditions of N,N^'-ethylen thiourea complexes of rhenium (V), establishment of mixture and physical and chemical properties of synthesized complexes