[en] Published in summary form only

[en] Described herein is an efficient protocol for the regioselective introduction of a vinyl trifluoromethylthioether to remote unactivated C(sp³)—H bonds. The cascade process involves the vinyl radical-mediated 1,5-hydrogen atom transfer (HAT) and remote vinyl migration. During the transformation, inert C—H and C—C bonds are consecutively cleaved under mild conditions. The reaction features good functional group tolerance, broad substrate scope, and high regio-/stereo-selectivity.

[en] A radioiodinated branched carbohydrate for tissue imaging. Iodine-123 is stabilized in the compound by attaching it to a vinyl functional group that is on the carbohydrate. The compound exhibits good uptake and retention and is promising in the development of radiopharmaceuticals for brain, heart and tumor imaging

[en] The well-known industrial dye 9,10-bis(phenylethynyl)anthracene and its derivatives have been widely studied in literature and have been functionally employed in various fields due to their rich photophysical properties. Here, we aim to explore the photophysical properties of their mono-substituted analogue. Six 9-phenylethynyl anthracenes were synthesized and the fluorescence emission properties and intramolecular charge transfer (ICT) abilities were compared with regard to various electron donating and withdrawing substituents at the para-position of the phenyl ring. The molecules were divided into two groups according to the absence and presence of ICT character according to the experimental observations, which was supported by theoretical calculations. One compound from each group was chosen to make a white light emitting (WLE) solution in DMSO. This solution was further used to prepare a WLE gel using Poly Vinyl Alcohol as the gelator. This gave an excellent CIE index of (0.31, 0.33). Further, fluorescence anisotropy studies show very good sensitivity of these compounds towards microviscosity of their immediate molecular environment. This property led to check the potential of these molecules in studies involving organized media. For example, N,N-dimethylamino substituted compound could sense the critical micellar concentration (CMC) of the bile salt Sodium deoxycholatein aqueous medium Additionally, the nitro substituted compound shows twisted ICT leading to drastic emission quenching and the hyper-sensitivity towards solvent polarity was used to quantitively sense moisture content in cyclic ether solvents like 1,4-Dioxane and THF using three parameters i.e., emission intensity decrease ratio, emission wavelength and lifetime values

No abstract available

[en] Shikimic acid is an important component in the production of several important drugs particularly the anti-influenza drug, Oseltamivir. Commercially, shikimic acid is extracted from the Chinese star anise or produced through the fermentation process by modified strain of E. coli. Regardless of the method of production, shikimic acid needs to be purified before it can be used for the intended purpose. Conventional method in the purification of shikimic acid usually involves the use of non-specific adsorbents that are less effective in isolating the shikimic acid. Molecularly imprinted polymer, being one of the la est adsorbents in separation science, offers an alternative technique that is more selective and specific than the conventional adsorption methods. This article is the exploratory work done to optimise the formulation for the preparation of mole ular imprinted polymer for shikimic acid that is 100 % compatible with aqueous systems. It emphasises particularly on the effects of various template: monomer: cross-linker ratios (TMX) on the performance of final polymer, including the preliminary evaluation results of the polymer performance. (author)

[en] Tritium NMR is a powerful spectroscopic technique whose understanding and applications have markedly expanded in the past few years. The growth of this area from 1990 to 2005 is reviewed. (author)

No abstract available

[en] A New polymer gel dosimeter containing N-Vinylcaprolactam monomer was prepared for radiotherapy. A medical linear accelerator was used to irradiate the gel samples to doses (2-20 Gy). A Minispec NMR relaxometer was used to measure the dose response. The results show the more amount of monomer in gel used, the higher dose sensitivity produced. Neither beam energy, nor dose rate show a visible influence on the irradiated gel and both data show a linear response fit up to 10 Gy. The unexposed as well as exposed gel samples are stable within 8 days. (author)

[en] There has been a dramatic growth in interest in the synthesis of poly(arylene vinylene)s due to their potential as emissive materials in light emitting diodes, LEDS, and a variety of routes have been utilised to prepare such polymers. We adopted the McMurry reaction to synthesis poly(1,3-phenylene diphenylvinylene) in our attempts to prepare polymers that would display a blue shifted emission as compared to that of the previously produced poly(4,4'-diphenylene diphenylvinylene) by incorporating phenyl ring with a meta linkage into the polymer chain. Polymers with relatively high molecular weight and narrow molecular weight distribution were produced when the as made samples were subjected to equilibrium fractionation. Samples with various molecular weights were characterised using UV-visible absorption spectroscopy and results correlating the characteristics of the polymer with UV-visible absorption are discussed. (author)