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AbstractAbstract
[en] The level is assessed of cellular autoreactivity against retinal antigens in patients with detachment of the retina. A test was selected which can record the first stage of the immunological response, i.e., the bond of sensitized lymphocytes with antigen (mixture of antigens in the form of crude extract), in this case with antigen from the human chorioretina. Two modifications of the test were used: the bond of 125I-labelled extract from the human chorioretina with isolated lymphocytes, and the bond of the same extract with lymphocytes of whole blood. Using the first modification, a total of 17 patients with detachment of the retina and 17 controls were examined. Usxng the second modification, 15 patients with detachment of the retina and 15 controls were examined. From the results of the test ensued that lymphocytes of patients with detachment of the retina do not differ from lymphocytes of controls in the capacity to bind 125I-labelled extract from the human chorioretina. The method is described in detail. (author)
Original Title
Vazba lymfocytu nemocnych odchlipenim sitnice se 125I znacenym extraktem z lidske chorioretiny
Primary Subject
Record Type
Journal Article
Journal
Ceskoslovenska Oftalmologie; ISSN 0009-059X; ; v. 38(6); p. 397-405
Country of publication
ANIMAL CELLS, BETA DECAY RADIOISOTOPES, BIOLOGICAL MATERIALS, BLOOD, BLOOD CELLS, BODY, BODY FLUIDS, CONNECTIVE TISSUE CELLS, DAYS LIVING RADIOISOTOPES, DISEASES, ELECTRON CAPTURE RADIOISOTOPES, EYES, INTERMEDIATE MASS NUCLEI, IODINE ISOTOPES, ISOTOPE APPLICATIONS, ISOTOPES, LEUKOCYTES, MATERIALS, NUCLEI, ODD-EVEN NUCLEI, ORGANS, RADIOISOTOPES, SENSE ORGANS, SOMATIC CELLS, TISSUES
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