[en] Patient with diffusely increased uptake in both kidneys on sup(99m)Tc methylene diphosphonate (sup(99m)Tc)MDP) or sup(99m)Tc Hydroxy methylene diphosphonate (sup(99m)TcHMDP) bone scintigram were evaluated. Among 3017 patients, 19(0.63%) showed this finding. These 19 patients included six with liver cirrhosis (three with primary hepatoma), two with lung cancer, two with leukemia, four with other malignant diseases, three with diabetes mellitus and two with anemia. Vascular damage of the kidneys and iron overload are considered to be probable major causes producing this findings