[en] The paper describes in general the production programmes of ⁹⁹Mo, ¹³¹I and ¹³³Xe at IRE by irradiating and reprocessing uranium targets. Given are technical data regarding the target technology, reactor and neutron flux requirements as well as the transport of irradiated targets. Different reactors are used for the irradiation of IRE's targets so that the different irradiation devices have been adapted to encounter the various conditions of the reactor characteristics and to obtain the desired activity by loading and unloading the targets independently of the reactor operation. This paper is reproduced under the explicit authorization of the Director General of the Institut National des Radioelements. (author). 6 refs, 6 figs