[en] ¹²³I-IMP SPECT was performed to study regional hemodynamics in basal ganglia infarction due to different pathological mechanisms. Non-lacunar infarction caused by main trunk occlusion or severe stenosis showed more extensive and marked reduction of peri-infarct and ipsilateral cerebral cortical blood flow, and demonstrated distinct differences compared with lacunar infarction on SPECT images. Inadequate perfusion or incomplete ischemic lesions undetected by X-ray CT were considered to be present in surrounding and cortical areas of non-lacunar infarction involving large vessel arterial disease. (author)