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AbstractAbstract
[en] Purpose: To analyze the results of T3N0M0 glottic carcinoma treated with radiotherapy, surgery, or both. Methods and Materials: The records were retrospectively reviewed of 97 patients with this tumor subsite and stage seen for treatment at the Queensland Radium Institute over a 29-year period. The results for radiotherapy with surgical salvage of failure ((XRT(SS))) were compared to those with surgery with or without radiotherapy ((SURG(SURG+XRT))). For those treated initially with radiotherapy alone, the results for different ranges of biologically equivalent doses were compared. These results were compared to those of other published studies. Results: The 5-year disease-specific survival rates for the (XRT(SS)) and (SURG(SURG+XRT)) groups were 50% and 58%, respectively; this difference is not significant. For the (XRT(SS)) group, there was a trend towards improved 5-year recurrence-free survival (73%) and 5-year disease-specific survival (86%) in those treated to a dose equivalent to 60-64 Gy in 2 Gy fractions, when compared with higher or lower dose equivalents. Conclusion: A group of patients with T3N0M0 glottic carcinoma is specified for which the option of radiotherapy offers a similar chance of survival to those treated surgically. More than 50% of the (XRT(SS)) survivors will retain their larynx
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Copyright (c) 1995 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)
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Journal Article
Journal
International Journal of Radiation Oncology, Biology and Physics; ISSN 0360-3016; ; CODEN IOBPD3; v. 31(2); p. 285-293
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