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[en] A priming irradiation with 0.45 Gy of X-rays, given 2 weeks prior to the challenging exposures, induces radio-resistance (decrease in bone marrow death rate after mid-lethal irradiations) in mice of C57BL/6 mice. This acquired radio-resistance appeared on day 9 and continued till day 17 after the priming irradiation, with a maximal on days 12-14 and diminished on day 21. The priming irradiation, given 14 days prior to the challenging exposure, increased endogenous spleen colonies on days 12-13 after exposure to 5.0 Gy. Effect of interval time between the priming and the challenging irradiations on the increase in endogenous spleen colonies was also examined. Significant increase of the colonies by the priming irradiation was observed when the interval time was 12-17 and 21 days. The results correspond to the increase of the survival rates on days 12-17 after the challenging irradiations. (author)
Source
Tanaka, Kimio; Takabatake, Takashi; Fujikawa, Katsuyoshi; Matsumoto, Tsuneya; Sato, Fumiaki (Inst. for Environmental Sciences, Rokkasho, Aomori (Japan)) (eds.); 367 p; ISBN 4-9980604-5-7; 
; 2003; p. 182-186; International symposium on biological effects of low dose radiation: Molecular mechanisms for radiation-induced cellular response and cancer development; Rokkasho, Aomori (Japan); 9-11 Oct 2002; 4 refs., 4 figs.
; 2003; p. 182-186; International symposium on biological effects of low dose radiation: Molecular mechanisms for radiation-induced cellular response and cancer development; Rokkasho, Aomori (Japan); 9-11 Oct 2002; 4 refs., 4 figs.