[en] The stable laser isotope facility will supply raw stable isotope material to produce radioisotope elements for medical and industrial applications. The medical stable isotope, Tl-203 was separated by the isotope selective optical pumping (ISOP) method native to the laboratory for quantum optics, KAERI. The extraction rate of 10 mg/hr was achieved from the separation chamber of 80cm x 80cm x 100cm dimension. The Yb-168 separation facility was improved in stability, durability, and efficiency. The old copper vapor pumping laser system was replaced with two 40W green DPSSL's. The tunable dye laser system was also improved in stability. The extraction rate was measured as 1.5 mg/hr in the improved system. The 200W infrared DPSSL system was also developed and used for photoionization of thallium isotopes. The adaptive optics and beam path control system was applied to the isotope separation facilities. Also the beam quality of the lasers was monitored and improved. To maintain constant isotope composition during reaction process, the wavelengths of tunable lasers are locked by being the mass composition information fed back into the oscillator control unit of the lasers. To optimize isotope separation process timely, the extractor surface is directly analyzed by laser irradiation and TOF mass spectrometer. And the final products in high purity is recovered in maximum by solution chemistry