[en] Objective: To evaluate the relationship between Multi-slices spiral (MSCT) perfusion and micro vessel density (MVD) in maxillofacial tumors. Methods: Thirty-one cases of maxillofacial tumors were studied with MSCT perfusion imaging before operation. The time-density curve, perfusion, time to peak (TTP), and Peak enhancement imaging (PEI) of tumors were calculated. MVD of the tumors was measured with immuno-histochemical method by means of detecting factor VIII in all the histologic specimens. Relativity analysis was carried between MSCT perfusion imaging parameters, perfusion curve types and MVD. Results: MVD of maxillofacial tumors were higher than normal tissue. MVD remarkably correlated with malignancy of the tumors. Perfusion and time to peak (TTP) correlated well with MVD (t=7.09, 4.10, P<0.05), but peak enhancement imaging (PEI) did not (t=0.76, P>0.05). Significant difference of MVD in three types of perfusion curve was found (F=8.09, P<0.05). The tumors in the rapid ascend style had the highest MVD. Conclusion: There are close correlations between MVD and perfusion, time to peak (TTP) and the shape of perfusion curve. MSCT perfusion imaging might evaluate MVD of maxillofacial tumors. It is a useful method in estimating the degree of angiogenesis and prognosis of maxillofacial tumors.(authors)