[en] Forensic botany is in high demand in Colombia in connection with plant material, mainly coca from illicit crops. The taxonomic study of the two species and four varieties of Erythroxylum P. Browne (Erythroxylaceae) cultivated in Colombia was carried out. Hybridization between E. coca and E. novogranatense and between the two varieties of E. coca is suggested, and important changes in the geographic distribution of all taxa are described. Both, hybridization and changes in distribution patterns are due to anthropic intervention.