[en] ⁶⁷Cu was produced with ⁷⁰Zn(p,a)⁶⁷Cu nuclear reaction in high current cyclotron cyclone-30. For high beam current irradiation on ⁷⁰Zn target, the electroplating method was successful and physical status of the ⁷⁰Zn was good, but unfortunately melting on the surface was found during 200μA proton irradiation on the target. The efficient chemical separation method for ⁶⁷Cu separation from irradiated ⁷⁰Zn target using solvent extraction (0.01% dithizone in CCl₄-HCl) followed by ion exchange method and the recycling process for the enriched ⁷⁰Zn material were developed. Several nuclear reactions with charged particle irradiation in the accelerator, i.e., ⁶⁸Zn(p,2p)⁶⁷Cu, ⁶⁷Zn(d,2p)⁶⁷Cu, ⁶⁴Ni(α,p)⁶⁷Cu and ⁷⁰Zn(p,α)⁶⁷Cu have been investigated for ⁶⁷Cu production. Based on consideration of the production yield and radioisotopes impurities level in ⁶⁷Cu solution, the characteristics of cyclotron beam in our institute, the latter nuclear reaction is best for ⁶⁷Cu production even though the target material, the enriched ⁷⁰Zn is very expensive.