[en] A metal organic framework (MOF) based adsorbent of type UiO-66 was hydrothermally prepared and applied to simultaneous sensing and removal of the asthma drug clenbuterol. The MOF possesses a large specific surface area (1460 cm²·g⁻¹) and a stable structure, and has a large adsorption capacity for clenbuterol (160 mg·g⁻¹). If clenbuterol binds to the MOF, the fluorescence of the sorbent (best measured at excitation/emission wavelengths of 290/396 nm) is quenched by up to 88%. Based on these findings, a fluorometric assay has been developed for the rapid determination of clenbuterol. The adsorption equilibrium of UiO-66 for CLB can be achieved at 60 min and the adsorption efficiency is above 80%. The method has a linear response in the 4.0 to 40 ng·mL⁻¹ concentration range, and the lower limit of detection is 0.17 μM. All of this indicates that UiO-66 is promising for simultaneous detection and the removal of CLB in water.

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