[en] Objective: To evaluate the safety and effectiveness of interventional treatment for pelvic lymphocele associated with deep vein thrombosis (DVT) of lower extremity after the operation for gynecologic malignant tumor. Methods: During last five years, a total of 12 patients with pelvic lymphocele associated with DVT of lower extremity after the operation for gynecologic malignant tumor received interventional treatment. The clinical data were retrospectively analyzed. The interventional procedures included catheter drainage, injection of hardening agent, implantation and retrieval of inferior vena cava filter, lower extremity vein stenting, etc. After the treatment, the patients were kept under close observation for the occurrence of serious complications and the improvement of clinical symptoms. Color Doppler ultrasonography and CT scan were employed to check the therapeutic results. Results: Inferior vena cava filter placement was performed in 12 patients, which was followed by puncture drainage of pelvic lymphocele; a total of 18 times of puncture drainage were carried out, including bilateral procedures in 5 patients, unilateral procedure in 7 patients and two times of puncture drainage in one patient. Filter retrieval was performed in 7 patients. In one patient, puncture of femoral artery was employed, and puncture of femoral artery was repeated after oppression hemostasis for 24 hours. Occlusion of drainage tube occurred in one patient, the occlusion was improved after replacement of the drainage tube. Left iliac vein stenting was adopted in one patient. After the treatment, in all patients no severe complications such as hemorrhage or pulmonary embolism occurred, and the clinical symptoms disappeared or were obviously improved. The patients were followed up for 3-47 months with a median time of 16 months. No recurrence of pelvic lymphocele was observed in all patients. Conclusion: For the treatment of lymphocele associated with DVT of lower extremity, interventional therapy is safe and effective. (authors)