[en] The nano-particles are not limited to the domain of physics rather it is now days used for the applications in information technology and bio-informatics whereby the assorted streams can be integrated. In this research paper, the analysis of the nano-particles related to the brain waves are taken so that the predictions on the datasets can be done for effective discovery and identification of the brain related diseases. This manuscript is having focus on the usage of machine learning based approach for the predictive analysis of the brain related diseases and found that the need to integrate the information technology to biological domains are quite mandatory for the medical sciences. (paper)