[en] Deficits in dopamine D2/D3 receptor (D2R/D3R) binding availability using PET imaging have been reported in obese humans and rodents. Similar deficits have been reported in cocaine-addicts and cocaine-exposed primates. We found that D2R/D3R binding availability negatively correlated with measures of body weight at the time of scan (ventral striatum), at 1 (ventral striatum) and 2 months (dorsal and ventral striatum) post scan in rats. Cocaine preference was negatively correlated with D2R/D3R binding availability 2 months (ventral striatum) post scan. Our findings suggest that inherent deficits in striatal D2R/D3R signaling are related to obesity and drug addiction susceptibility and that ventral and dorsal striatum serve dissociable roles in maintaining weight gain and cocaine preference. Measuring D2R/D3R binding availability provides a way for assessing susceptibility to weight gain and cocaine abuse in rodents and given the translational nature of PET imaging, potentially primates and humans.

[en] Mogas has been an alternative to leaded fuel since 1964 when Experimental Aircraft Association (EAA) began testing on it. However, in order for mogas to be used in aircraft engines and air frame modification, approval via the Supplemental Type Certificate (STC) authorization from Federal Aviation Administration (FAA) is mandatory. Cessna on 01.06.2010 evaluated alternative fuels with ethanol based fuels approved by FAA STCs for use in some single engine airplanes. However, Cessna’s tests discovered that ethanol based gasoline cannot be viewed as an option to 100LL avgas. The test likewise proposed that operational safety might be in jeopardy if usage of these fuels containing ethanol is continued. Cessna outlined a few problems in MOGAS; MOGAS needs fuel flow increase of 40% compared to AVGAS, MOGAS fuel is incompatible with some fuel system components, possible hazardous influence of electric fuel pumps by adding internal wear causing unexpected spark generation, MOGAS is incompatible with some fuel gauging systems and cause be able to incorrect fuel amount signs on the indicator, dissolve large amounts of water at conditions down to -77°F, impeding detection and removal of water from the fuel system, possible blockage of fuel filters and fuel flow and possible heavy losses from evaporation. This paper reviews concerns when using MOGAS in aircraft. (paper)

[en] Since there is a developing practice of utilizing automotive fuels as flight fuel, there are higher chances of dangerous scenarios, particularly in the operation of piston aircraft engines. The use of motor vehicle gas (MOGAS) or aviation gas (AVGAS) in the operation of aviation piston engine increases the risk of vapour locking. A statistical examination of European aviation industry indicates that around 20,000 aircraft are affected either specifically or conceivably by the different negative impacts of gasoline blended with ethanol. Particularly, for most contemporary carburettor engines, there are risks associated with ethanol-admixed fuels that have potential to upset engine operation. The danger of vapour locking, which is the generation of gas bubbles inside the fuel system causing an impairment of fuel movement in the engine, is well documented particularly by studies on aircraft using MOGAS. Contrasted with AVGAS, MOGAS is inclined to demonstrate this phenomenon. Vapour lock is perhaps the leading serious problem that ought to be addressed if MOGAS is to be used as a substitute for AVGAS. Vapour lock problem is critical because it causes malfunctions to aircraft engines. Thus, an understanding of vapour handling ability of small aircraft is essential to establish safe operating confines at existing fuel temperature and pressures. (paper)

[en] There are two categories of aircraft engines, namely, piston and gas turbine engines. Piston engine extracts energy from a combustion compartment through a piston and crank apparatus that engages the propellers, which in turn, provides an aircraft the needed momentum. On the other hand, gas turbine engine heats a compressed air in the combustion compartment resulting in propulsion that drives an aircraft. Piston engine aircrafts might appear small but together thousands of piston engine aircraft, which encompasses a bulk of the general aviation fleet, present a considerable health threat. That is because these aircraft, which depend on avgas and mogas to run, comprise major remaining sources of lead emissions. People exposed to even small levels of lead, particularly children, have tendencies to suffer from cognitive and neurological harm. Dissimilar from commercial airliners that do not utilize leaded fuels, piston engine aircraft account for nearly half of the lead discharge in skies. But, what is the extent of the impact caused by these airborne emissions on the country’s economy and public health? To answer this query, a thorough literature review on emissions of piston engine aircraft ought to be undertaken. This article conducts a literature review on emissions of piston engine aircraft using avgas as fuel and mogas as fuel. (paper)

[en] Aviation gasoline (Avgas) has remained unchanged for seventy years and the existing fleet of piston aircraft was designed to be compatible with its chemical and physical properties to achieve superior levels of safety. Tetra-ethyl lead (TEL) is an octane-enhancing metal additive used in aviation gasoline to prevent knocking. Studies have shown that lead causes brain damage in children reducing their IQ and cardiovascular difficulties and kidney failure in adults. Friends of the Earth (FOE) petitioned the Environmental Protection Agency (EPA) in 2006 to make a finding that lead emissions from general aviation (GA) aircraft cause to public health endangerment or carry out studies and issue a report on its findings. PAFI was set up by Federal Aviation Administration (FAA) to find most suitable unleaded replacements for Avgas to recognize best unleaded fuel that have the capacity to in fact satisfy the requirements of the present aircraft fleet while additionally considering the creation, dispersion, cost, availability, environmental impacts. This study will technically review PAFI and broaden the limited knowledge on piston aviation fuels in Malaysia by giving a comprehensive analysis and possible gap in reciprocation aviation engine market in Malaysia. (paper)

[en] In an attempt to bring in sustainable energy resources into the current combustibles mix, recent European legislations make obligatory the addition of biogenic fuels into traditional fossil gasoline. The preferred biogenic fuel, for economic reasons, is predominantly ethanol. Even though likened to fossil gasoline constituents, ethanol has a dissimilar chemical formulation that may lead to a potentially hazardous physicochemical phenomenon, particularly in the presence of water. Owing to increased financially driven propensity to utilize motor vehicle gasoline as aviation gasoline fuel, this may result in potentially hazardous situations, specifically in running smaller or compact General Aviation aircraft. The potential risks posed by ethanol admixtures in aircraft are phase separation and carburettor icing. Gasoline mixed with ethanol is also prone to an increased vulnerability to vapor lock that happens when fuel turns into vapor in the fuel pumps due to high temperatures and lessened ambient pressure at high altitudes. This article provides a literature review on phase separation issues in aviation gasoline fuel and motor gasoline fuels in aviation. (paper)