[en] The SOLEIL synchrotron is organizing, with the next annual SOLEIL Users' Meeting (18-19 January 2012) gathering about 350 international scientists each year, a satellite workshop entitled: 'Biology and medicine: from fundamental research ta diagnosis'. The workshop aims to bring together medical doctors, bio-physicists/-chemists, structural and cell biologists as well as synchrotron scientists. The participants in biology will highlight recent studies that combine complementary methods in order to understand the complexity of living organisms and their functional mechanisms, from atomic resolution macromolecular structures to cell and tissue imaging. In medicine, synchrotron radiation related techniques are now used in cutting edge investigations for diagnosis and fundamental understandings of diseases. Recent advances in medical applications of SOLEIL synchrotron radiation related techniques to the study of various diseases such as urolithiasis, liver pathologies or endocarditis will be presented. This book gathers the abstracts of 22 talks and 11 posters: Application of Synchrotron Based FTIR Spectroscopy in Medicine - Is There a Niche? Calcifications in Human Osteoarthritic Articular Cartilage: Ex Vivo Assessment of Calcium Compounds Using Xanes Spectroscopy. Synchrotron Infrared and Fluorescence Microspectroscopies to Assess the Diffusion and Effects of Antibacterial Agents in Bacterial Communities. Quantitative Imaging of Regional lung Function Using Synchrotron Radiation Computed Tomography: Present Status, Future Orientations. When the Sun Highlights the Randall's Plaques and Kidney Concretions. Influence of Green Tea on Oxalate Kidney Stones: an ex vivo Investigation of the Ultrastructure. Qualitative and Quantitative Assessment of Liver Steatosis Using infrared Microspectroscopy. Chemical Analysis of Thyroid Microcalcifications: Can it Have an Impact on Thyroid Diseases Care? Micro-tomography Using Synchrotron Radiation: New Developments at the Microscopic Level to Study Bone. Investigation of the Bone Osteocyte Network from Synchrotron Nano-CT. Synchrotron Radiation Therapy, Preparation of a Clinical Trial. Structures of Two Lactococcal Phage Baseplates - Their Mechanism of Activation Deciphered Using Hybrid Methods. Integrative Structural Analysis of Transcription and Translation Complexes. Structural Study of Telomeres Molecular Architecture. Regulatory Mechanisms in Toxin-Antitoxin Modules. Scanning Hard X-ray Nano-imaging in Biology and Life Sciences: Tissular and Subcellular Topography, and Speciation of Trace Elements, Transition Metals. Coherent X-ray Tomography at the Synchrotron: Multimodal 3D imaging with High Resolution and Sensitivity. From the Fibrinogen Structure to the Mechanism of Fibrin Polymerization: HPLC-SAXS and Stopped-Flow/MALLS/SAXS at the SOLEIL SWING Beamline. Structure of Inclusions of Huntington Disease Brain Revealed by Synchrotron infrared Microspectroscopy. Analyzing Metal Binding Sites in Proteins Using (far) Infrared Spectroscopy: Why and How? Multi-Drug Resistance in Bacteria: Study of the Antibiotics Uptake in Resistant Bacterial Strains by DUV Fluorescence Microspectroscopy. Titanium Dioxide Nanoparticle Uptake and Impact on Gastro-Intestinal and Lung Models. Zn(II) Coordination to Human and Murine Amyloid-β Peptides involved in Alzheimer's Disease. Molecular mechanisms of PGC-1 α Coactivator Recognition by Estrogen-Related Receptors. Role of a Hydrophobic Cavity in Urate Oxidase Enzymatic Activity Revealed by X-ray Crystallography and Enzymatic Assay under High Hydrostatic Pressure and Under inert Gas Moderate Pressure. Analysis of Liver Steatosis Using Infrared Microspectroscopy on Tissue Sections. Structure-Photophysics Relationships at Acidic pH of the Cyan Fluorescent Protein. Yeast Lipid Bodies Under Sunlights Dynamic and Structural Studies Using SMIS and DISCO Beamlines. Nanoassemblies of Nucleoside Analogues Coupled to Terpenoids: Structural Analysis. Need for New imaging Tools to Study the internalization and the Localization of Nanoparticles into Cells. Structural basis for the functional versatility of β-Thymosin/WH2 Domains in Actin Assembly. Nanotoxicity of Nanodrugs Using SRCD (SOLEIL): Tests on Human Proteins. DISCO: Synchrotron Radiation Circular Dichroism at SOLEIL