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Haddad, F.; Cherel, M.; Bardies, M.; Auduc, S.; Devilder, R.; Thomas, Y.; Chatal, J.F.; Barbet, J.; Martino, J., E-mail: haddad@subatech.in2p3.fr
Report on the Technical Meeting on Therapeutic Radiopharmaceuticals2009
Report on the Technical Meeting on Therapeutic Radiopharmaceuticals2009
AbstractAbstract
[en] ARRONAX, acronym for ''Accelerator for Research in Radiochemistry and Oncology at Nantes Atlantique'', is a high energy and high intensity cyclotron. It will turn into operation in September 2009 in Nantes (France). It is mainly devoted to the production of radionuclides for medicine. A priority list based on the capability of the machine as well as on the need expressed by the European medical community through a questionnaire has been set. It contains isotopes for imaging (82Sr/82Rb and 68Ge/68Ga generators and 64Cu, 44Sc, 55Co) and for therapeutic use (67Cu, 47Sc and 211At). In this list, a special attention has been paid to dosimetry, both by giving lower scores of interest to radionuclides with undesirable emissions, such as high energy gammas, and by promoting β+/β- couples of radionuclides (64Cu/67Cu and 44Sc et 47Sc). Indeed, pre-therapeutic dosimetry is essential in the development of new radiolabeled therapeutics and PET imaging should prove more precise and accurate in calculating radiation doses received by critical organs and tumors. Arronax and its partners will also devote a large effort to develop targeted alpha-radionuclide therapy. In particular, a radioimmunotherapy project using 211At coupled to a specific monoclonal antibody will start this autumn to treat prostate cancer patients with high risk of relapse. ARRONAX is an important part of the project since it will have to produce astatine in large amounts on a regular basis. (author)
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International Atomic Energy Agency, Industrial Applications and Chemistry Section, Vienna (Austria); 113 p; 2009; p. 37; Technical Meeting on Therapeutic Radiopharmaceuticals; Vienna (Austria); 16-20 Nov 2009; Abstract only
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ACCELERATORS, ALKALINE EARTH ISOTOPES, ALPHA DECAY RADIOISOTOPES, ANTIBODIES, ASTATINE ISOTOPES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BODY, COBALT ISOTOPES, COPPER ISOTOPES, CYCLIC ACCELERATORS, DAYS LIVING RADIOISOTOPES, DISEASES, DOSES, DRUGS, ELECTRON CAPTURE RADIOISOTOPES, ELEMENTS, EVEN-EVEN NUCLEI, GALLIUM ISOTOPES, GLANDS, HALOGENS, HEAVY NUCLEI, HOURS LIVING RADIOISOTOPES, IMMUNOTHERAPY, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, MALE GENITALS, MATERIALS, MEDICINE, MINUTES LIVING RADIOISOTOPES, NONMETALS, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ODD-ODD NUCLEI, ORGANS, RADIOACTIVE MATERIALS, RADIOISOTOPES, RADIOLOGY, RADIOTHERAPY, RUBIDIUM ISOTOPES, SCANDIUM ISOTOPES, STRONTIUM ISOTOPES, THERAPY, USES
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