[en] 99m Tc is widely acceptable for its many reasonable criteria in diagnostic use for different clinical Nuclear Medicine studies. Since very beginning of the Nuclear Medicine services in our country, 99m Tc was available form the imported 99m Tc generator form abroad. From September 2000 to December 2000 at Nuclear Medicine Centre (NMC), Comilla we have received eight generators from Radioisotope Production Division (RIPD), Institute of Nuclear Science and Technology (INST), Atomic Energy Research Establishment (AERE), Savar, Bangladesh for Clinical Nuclear Medicine studies. Out of eight generators five generators showed satisfactory performance on elution dose measurement with reference dose, three differs with the reference dose. During the elution dose measurement with reference dose. Three differs with the reference dose. During the elution procedure, the exposure rate was also within the safe limit. Sometimes a second elution was recorded, when available activity on the first elution performance was not satisfactory. This may be due to improper preparation of vacuum vials or incorrect referred activity or any other causes. 170 patients were studied by 99m Tc with intravenous injection available form these generators. Out of them Thyroid Scan (61), Renogram (45), Liver Scan (23) and Bone Scan (14) were remarkable. In clinical use with 99m Tc from these generator, image quality was satisfactory. No pyrogen toxicity or any other adverse effect was observed in any case. (authors) 3 figs., 5 refs