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AbstractAbstract
[en] Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycaemia in childhood. 18−Fluoro-L-dihydroxy-phenylalanine (18F-DOPA) positron emission tomography (PET) can detect areas of increased activity in the pancreas and may differentiate focal from diffuse CHI. We here report the case of a girl who complained of recurrent episodes of severe hypoglycaemia despite previous partial pancreatectomy. To evaluate the need for additional surgical intervention, we performed 18F-DOPA PET/computed tomography (CT), which showed a focal lesion corresponding to the anatomical region of the pancreatic tail. On the other hand, abdominal magnetic resonance imaging (MRI) clearly demonstrated that the 18F-DOPA uptake was in a loop of bowel occupying the previous surgical bed. Our case highlights that bowel uptake can be a possible pitfall in the interpretation of 18F-DOPA PET/CT in children affected by CHI, suggesting that when 18F-DOPA PET/CT results do not fit the clinical picture, magnetic resonance imaging (MRI) may allow a more accurate correlation of the radiotracer activity with the underlying anatomical or pathological structure
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Source
Country of input: Korea, Republic of; 4 refs, 2 figs
Record Type
Journal Article
Journal
Nuclear Medicine and Molecular Imaging (2010 Print); ISSN 1869-3474; ; v. 51(4); p. 362-363
Country of publication
AGE GROUPS, ANIMALS, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BIOLOGY, BODY, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DIGESTIVE SYSTEM, EMISSION COMPUTED TOMOGRAPHY, ENDOCRINE GLANDS, FLUORINE ISOTOPES, GLANDS, HOURS LIVING RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LIGHT NUCLEI, MAMMALS, MAN, MEDICINE, NANOSECONDS LIVING RADIOISOTOPES, NUCLEI, ODD-ODD NUCLEI, ORGANS, PRIMATES, RADIOISOTOPES, TOMOGRAPHY, VERTEBRATES
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