[en] The purpose of the present study was to investigate the degree and clinical relevance of synovitis in craniomandibular dysfunction. In total, 140 temporomandibular joints were examined using a 3 T MRI scanner. Quantitative analysis of synovial enhancement was performed and interrelated with arthrosis deformans, degenerative disc disease, joint effusion, bone marrow edema and restriction of motion. We found a statistically high and significant correlation between the degenerative changes as mentioned above and the intensity of synovial enhancement. The study shows that typical MRI findings in CMD patients are often combined with signs of synovitis. Presumably joint inflammation has an effect on the clinical signs and symptoms and also the prognosis of CMD. These results should be taken into consideration when selecting treatment.