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Gutierrez, M.
Universidad de la Republica, Facultad de Ciencias, Centro de investigaciones nucleares, Montevideo (Uruguay)2012
Universidad de la Republica, Facultad de Ciencias, Centro de investigaciones nucleares, Montevideo (Uruguay)2012
AbstractAbstract
[en] Multiple myeloma (M M) is a neoplasm characterized by infiltration of malignant plasma cells in the bone marrow, and is associated with high levels of monoclonal protein component or M. One of the key molecules involved in the pathogenesis of M M is the interleukin I L-6. This is a polypeptide belonging to the class of cytokines helical, having antiinflammatory activity and pro inflammatory and is secreted by a wide variety of cells. It has been found that high levels of I L-6 are directly related to the growth and survival of M M cell proliferation therefore I L antagonists may be of potential use therapeutic and diagnostic purposes. The Tocilizumab (Act emr To®) is a humanized monoclonal antibody directed against the receptor, both soluble and membrane I L-6 blocking cell signaling mediated by this. The possibility of combining Tocilizumab a gamma emitting isotope would determine l to topography where an increased expression of I L, with the consequent possibility that this associated with an infectious or neoplastic process is observed. In this way it could be used as a diagnostic method. Based on the above, the present work aims to develop the marking and evaluation of 99m Tc Tocilizumab, which could be used as diagnostic radiopharmaceutical to determine the location of the lesion and its extension, both debut in monitoring patients with multiple myeloma
Original Title
Desarrollo y evaluacion biologica de 99m Tc-tocilizumab como agente de imagen molecular en mieloma multiple
Primary Subject
Source
2012; 79 p; Available https://www.colibri.udelar.edu.uy/handle/123456789/1426; Tesina de graduacion de la licenciatura de Bioquimica; Thesis (Lic. de Bioquimica)
Record Type
Miscellaneous
Literature Type
Thesis/Dissertation
Report Number
Country of publication
ANIMAL CELLS, ANIMAL TISSUES, ANTIBODIES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BODY, CONNECTIVE TISSUE CELLS, DEVELOPING COUNTRIES, DIAGNOSTIC TECHNIQUES, DISEASES, DRUGS, GROWTH, GROWTH FACTORS, HEMATOPOIETIC SYSTEM, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, LATIN AMERICA, MATERIALS, MEDICINE, MEMBRANE PROTEINS, MITOGENS, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANS, PEPTIDES, PROTEINS, RADIOACTIVE MATERIALS, RADIOISOTOPES, RADIOLOGY, SOMATIC CELLS, SOUTH AMERICA, TECHNETIUM ISOTOPES, YEARS LIVING RADIOISOTOPES
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Mejia Gutierrez, M.
Alternative agricultures: Emphasis in contributions of the people of field of southwestern sector of Colombia1995
Alternative agricultures: Emphasis in contributions of the people of field of southwestern sector of Colombia1995
AbstractAbstract
[en] It offers a definition of alternative agricultures. Some antecedents are mentioned about the evolution of the Colombian movements from the chemical agriculture toward alternative forms. Some Colombian experiences are enumerated, making emphasis in people of field of the southwestern sector of the country contributions. Some conclusions settle down
Original Title
Agriculturas alternativas: Enfasis en aportes de gente de campo del sector suroccidental de Colombia
Primary Subject
Secondary Subject
Source
Corporacion para la Conservacion del Medio Ambiente; [200 p.]; 1995; p. 75-85; Corporacion para la Conservacion del Medio Ambiente - Universidad Pedagogica y Tecnologica de Colombia - Medio ambiente y agricultura ecologica; Bogota (Colombia); International congress of Biological Agriculture and environment; Bogota (Colombia); 25-27 May 1994
Record Type
Book
Literature Type
Conference
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Garcia Gutierrez, M.
Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain)1994
Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain)1994
AbstractAbstract
[en] This report presents the radionuclide migration in granitic rocks used for radioactive waste storage. This project is developed in El Berrocal (Spain). The author studies the absorption process, applies the transport equation, the column migration and analyzes the curves
Original Title
Experiencias preliminares de migracion de radionucleidos con materiales graniticos: El Berrocal (Espana)
Primary Subject
Source
1994; 110 p
Record Type
Report
Report Number
Country of publication
ACTINIDES, ALKALI METALS, DEVELOPING COUNTRIES, ELEMENTS, ENVIRONMENTAL TRANSPORT, EUROPE, IGNEOUS ROCKS, MANAGEMENT, MASS TRANSFER, METALS, PLUTONIC ROCKS, REACTOR FUELING, REPROCESSING, ROCKS, SEMIMETALS, SEPARATION PROCESSES, SORPTION, STORAGE, TRANSURANIUM ELEMENTS, WASTE MANAGEMENT, WASTE STORAGE
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Bustamante Gutierrez, M. G.
Universidad de Costa Rica (Costa Rica)2000
Universidad de Costa Rica (Costa Rica)2000
AbstractAbstract
[en] Analytic methods were implemented based on valuations acid-base and redox for the quantitative determination of sodium hidroxid, iodine and iron chloride III, like part of a system of quality for the technical specifications of these reagents. The planning of its system of quality includes two fundamental parts: insurance and control of quality. In the insurance part the state of operation of the team that you uses settled down, gauges the one that achieve to maintain under the supervision of a single operator (electronic equip and glassware) and the design of the appropriate documents settled down to carry out the periodic supervision of the acting of the same ones and other aspects characteristic of the system (experimental results). Also protocolized and validated the analytic methods to use following the approaches of precision given by ASTM, organism whose methodologies are recognized in the country like official; other procedures, as that of calibration of the volumetric equipments, they were also protocolized. In the part of control of quality, the limits settled down and procedures were applied the scales and used other, to the necessary distilled water to carry out the determinations and to the used chemical reagents. With base in the obtained results you determines that the analyzed reagents fulfill the specifications of ACS (and with those reported by the maker) at the same time settled down that the laboratory 09 of the Chemistry School, used in a large part of development of this project, it didn't fulfill the necessary requirements so that it works as laboratory of control of quality. As an alternative, the administration of the School outlines as solution the use of the Laboratory of Insurance of the Quality from the Unit of Service to the Industry for such end
[es]
Se implementaron metodos analiticos basados en valoraciones acido-base y redox para la determinacion cuantitativa de hidroxido de sodio, yodo y cloruro de hierro III, como parte de un sistema de calidad para las especificaciones tecnicas de estos reactivos. El planeamiento de su sistema de calidad incluyo dos partes fundamentales: aseguramiento y control de calidad. En la parte de aseguramiento se establecio el estado de operacion del equipo que se utilizo, se calibro el que se logro mantener bajo la supervision de un solo operador (equipo electronico y cristaleria) y se establecio el dise de los documentos adecuados para llevar a cabo la supervision periodica del desempe de los mismos y otros aspectos propios del sistema (resultados experimentales). Tambien se protocolarizaron y validaron los metodos analiticos a utilizar siguiendo los criterios de precision dados por ASTM, organismo cuyas metodologias son reconocidas en el pais como oficiales; otros procedimientos, como el de calibracion del equipo volumetrico, tambien fueron protocolizados. En la parte de control de calidad, se establecieron los lineamientos y procedimientos se aplicaron las balanzas y otros equipos utilizados, al agua destilada necesaria para llevar a cabo las determinaciones y a los reactivos quimicos utilizados. Con base en los resultados obtenidos se determino que los reactivos analizados cumplen con las especificaciones de ACS (y con los reportado por el fabricante). A la vez se establecio que el laboratorio 09 de la Escuela de Quimica, utilizado en gran parte de desarrollo de este proyecto, no cumplio con los requisitos necesarios para que funcione como laboratorio de control de calidad. Como una alternativa, la administracion de la Escuela planteo como solucion el uso del Laboratorio de Aseguramiento de la Calidad de la Unidad de Servicio a la Industria para tal fin. (author)Original Title
Organizacion de un sistema de garantia de calidad para el control de especificaciones de reactivos quimicos
Primary Subject
Source
2000; 66 p; Available from Biblioteca Luis Demetrio Tinoco, Universidad de Costa Rica; Tabs., figs., refs., ills.; Thesis (Lic.)
Record Type
Miscellaneous
Literature Type
Thesis/Dissertation
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Gutierrez M, O. E.
Instituto Tecnologico de Toluca, Metepec, Estado de Mexico (Mexico)2011
Instituto Tecnologico de Toluca, Metepec, Estado de Mexico (Mexico)2011
AbstractAbstract
[en] The synthesis of iron nanoparticles for the removal of metallic ions in polluted waters has been during the last years study topic for different world organizations. This work presents a synthesis method of conditioned coal with iron nanoparticles starting from the use of leaves of pineapple crown, with the purpose of using it in arsenic removal processes in aqueous phase. For the synthesis of this material, the leaves of the pineapple crown were used like supports structure of the iron nanoparticles. First, the pyrolysis appropriate temperature was determined. For the preparation of the support material, this had contact with a ferric nitrate and hexamine solution, because the preparation of the material and the coal synthesis were realized during the pyrolysis process, where the hexamine molecules and the ferric nitrate react, causing the reduction of the iron particles and their dispersion on the support material, obtaining as product a conditioned coal with iron nanoparticles. For the characterization of the materials were used techniques as: Scanning electron microscopy, Transmission electron microscopy, X-Rays Diffraction), X-Ray photoelectron spectroscopy and Moessbauer spectroscopy; moreover was determined the isoelectric point and the density of surface sites. The arsenic sorption capacity of the materials was evaluated by means of the methodology type lots where was determined the sorption kinetics and isotherms in terms of arsenic concentration and mass. (Author)
Original Title
Sintesis y caracterizacion de nanoparticulas de hierro para la remocion de arsenico en agua
Primary Subject
Source
2011; 88 p; Thesis (chem. eng.)
Record Type
Miscellaneous
Literature Type
Thesis/Dissertation
Report Number
Country of publication
CARBONACEOUS MATERIALS, CHEMICAL REACTIONS, COHERENT SCATTERING, DECOMPOSITION, DIFFRACTION, DIMENSIONLESS NUMBERS, DISPERSIONS, ELECTRON MICROSCOPY, ELECTRON SPECTROSCOPY, ELEMENTS, ENERGY SOURCES, FOOD, FOSSIL FUELS, FRUITS, FUELS, HOMOGENEOUS MIXTURES, MATERIALS, METALS, MICROSCOPY, MIXTURES, NITROGEN COMPOUNDS, OXYGEN COMPOUNDS, PHOTOELECTRON SPECTROSCOPY, PHYSICAL PROPERTIES, REMOVAL, SCATTERING, SEMIMETALS, SPECTROSCOPY, THERMOCHEMICAL PROCESSES, TRANSITION ELEMENTS
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Piping processes are controlled by many interacting factors, such as the index of dispersion and the sodium content, SAR and ESP. To it is necessary to join the density of cracking and the slope of the hillsides on which it develops. In the study area climatic characteristics together with soil structure and chemical and mineralogical composition of the substrate has a key role in Pipings formation. Cracking is linked to the presence of dispersive clays with high contents in SAR and ESP, which give the rates of swelling until 12%. The process presence of piping is linked to two concrete situations: the massive intermediate levels of the intermediate Holocene filling sediments and the sediments deposited by the gullies: whereas in the tertiary materials it does not manage to develop. The size and scale of the pipes studied show a clear relationship among the level thickness, slope and hydraulic gradient. In the Holocene landfills the principal bounding factor is the levels thickness since the lower laminated levels do not facilitate the continuity in depth of the process due to the high number of discontinuities, generating centimeter-scale conduits that are always on duty to the drainage network. (Author) 5 refs.
Original Title
Influencia de los procesos de sofusion (piping) en la evolucion del modelado. Bardenas Reales (Navarra)
Primary Subject
Source
Romero Diaz, A.; Belmonte Serrato, F.; Alonso Sarria, F.; Lopez Bermudez, F. (eds.); 732 p; ISBN 978-84-8371-888-9; 
; 2009; p. 223-226; Ediciones de la Universidad de Murcia; Murcia (Spain); Advances in Studies on Desertification; Murcia (Spain); 16-18 Sep 2009
; 2009; p. 223-226; Ediciones de la Universidad de Murcia; Murcia (Spain); Advances in Studies on Desertification; Murcia (Spain); 16-18 Sep 2009
Record Type
Book
Literature Type
Conference
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Gutierrez, M. C.; Barrera, R.
Junta de Energia Nuclear (JEN), Madrid (Spain)1978
Junta de Energia Nuclear (JEN), Madrid (Spain)1978
AbstractAbstract
[en] As result of quantitative studies on gamma-radiolysis of DMSO at a dose range of 90-850 Mrads, constant G values have been obtained for the following radiolysis compounds: G(-DMSO) - 6.7 ±0.2; G(dimethyl sulphide) - 3.4 ±0.3; G(methane) - 0,75 ± 0.04; G(dimethyl disulphide) -0.33 ±0,03; G(tri methylsulphonium methanesulphonate) - 0.26 ± 0,01; G(methyl methanethiosulphonate) - 0,25 ±0.02; G(dimethyl sulphona)-0.21±0.02; G(H2)-0.18±0.02; and G(propane)--0.0092±0.0007. Initial G values have been obtained for other identified compounds: Gi(ethane)-0,46; Gi(CO)-0.052; and Gi(CO2)-0.030. Possible mechanisms on the radiolysis process are proposed. (Author) 17 refs
Original Title
Gamma-Radiolisis del dimetilsulfoxido II. Rendimientos radioloticos y posibles mecanismos
Primary Subject
Source
1978; 29 p
Record Type
Report
Report Number
Country of publication
ALKANES, ALKYL RADICALS, CARBON COMPOUNDS, CARBON OXIDES, CHALCOGENIDES, CHEMICAL RADIATION EFFECTS, CHEMICAL REACTIONS, DECOMPOSITION, ELECTROMAGNETIC RADIATION, EVALUATION, HYDROCARBONS, IONIZING RADIATIONS, ORGANIC COMPOUNDS, ORGANIC SULFUR COMPOUNDS, OXIDES, OXYGEN COMPOUNDS, RADIATION EFFECTS, RADIATIONS, RADICALS, SULFOXIDES, SULFUR COMPOUNDS
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Garcia Gutierrez, M.
Centro de Investigaciones Energeticas, Medioambientales y Technologicas (CIEMAT), Madrid (Spain)2000
Centro de Investigaciones Energeticas, Medioambientales y Technologicas (CIEMAT), Madrid (Spain)2000
AbstractAbstract
[en] This report presents a deterministic and probabilistic databases for application in Performance Assessment of a high-level radioactive waste disposal. This work includes a theoretical description of sorption, diffusion and solubility phenomena of radionuclides in geological media. The report presents and compares the databases of different nuclear wastes management agencies, describes the materials in the Spanish reference system, and the results of sorption diffusion and solubility in this system, with both the deterministic and probabilistic approximation. The probabilistic approximation is presented in the form of probability density functions (pdf). (Author) 52 refs
Original Title
Base de Datos de Sorcion, Difusion y Solubilidad para la Evaluacion del Comportamiento
Primary Subject
Source
2000; 96 p
Record Type
Report
Report Number
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Garcia Gutierrez, M.
El Berrocal project: characterization and validation of natural radionuclide migration processes under real conditions on the fissured granitic environment1996
El Berrocal project: characterization and validation of natural radionuclide migration processes under real conditions on the fissured granitic environment1996
AbstractAbstract
[en] Starting from a fresh ground granite sample several fractions were obtained that correspond to the following size ranges: 250 mu m>x>125 mu m, 125 mu m>x>63mu m, 63 mu m>x>40 mu m, and x <40 mu m. In the first three fractions the light and heavy constituents were also separated using liquids of different densities. The lighter components were mainly Quartz (Q), Potassium Feldspar (KFd, Microcline) and Plagioclases (Plag., Albite); the heavier were Biotite, Muscovite and Chlorite (and other possible accessory minerals such as Andalusite and Apatite). At the same time that light constituents were separated in the three following fractions: a) Q+KFd+Plag b) Q+Plag c) KFd. (Author)
Primary Subject
Secondary Subject
Source
4 v; 1996; p. 7-27; ENRESA; Madrid (Spain)
Record Type
Book
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Some triangular slope facets are localized to the south of Bardenas Reales (central-west of Ebro Basin), elaborated on Tudela Formation deposits, Aragonian in age. Three of them have been dated by OSL resulting on ages of 35,588±2,488 yr. BP, 35,355±2,446 yr. BP and 40.185±2,411 yr. BP. The origin of these facets is ought to an alternation between accumulation and incision phases produced by vegetation cover variation percentage. Those vegetation cover changes are estimated to be due to climatic changes. (Author) 21 refs.
Original Title
Facetas triangulares de ladera en la region de Tudela (Depresion del Ebro, Navarra, Espana)
Primary Subject
Source
Romero Diaz, A.; Belmonte Serrato, F.; Alonso Sarria, F.; Lopez Bermudez, F. (eds.); 732 p; ISBN 978-84-8371-888-9; ; 2009; p. 315-318; Ediciones de la Universidad de Murcia; Murcia (Spain); Advances in Studies on Desertification; Murcia (Spain); 16-18 Sep 2009
; 2009; p. 315-318; Ediciones de la Universidad de Murcia; Murcia (Spain); Advances in Studies on Desertification; Murcia (Spain); 16-18 Sep 2009
Record Type
Book
Literature Type
Conference
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
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