[en] The scientific validity of a method requires in final analysis that the results are independent of the user. This statement which would in other circumstances appear tautological is actually controversial in nuclear medicine, where the skill of the operator tends to be valued. But if the operator is interested in the outcome of the quantitative analysis and operator bias is allowed, the value of quantitation per se is lost. We have developed a set of algorithms which allows full automation in the analysis of ventilation-perfusion studies and in the detection of left-to-right intracardiac shunting, and which except for the identification of the valve planes, allows full automation in the processing of nuclear angiocardiography (First Pass or ECG Gated) for LV function analysis