[en] In beam halo experiments, it is very important to correctly characterize the RFQ output proton beam. In order to simulate the beam dynamics properly, we must first know the correct initial beam parameters. We have used two different methods, quadrupole scans and multi-wire scanners to determine the transverse phase-space properties of the proton beam. The experimental data were analyzed by fitting to the 3-D nonlinear simulation code IMPACT. For the quadrupole scan method, we found that the RMS beam radius and the measured beam-core profiles agreed very well with the simulations. For the multi-wire scanner method, we choose the case of a matched beam. By fitting the IMPACT simulation results to the measured data, we obtained the Courant-Snyder parameters and the emittance of the beam. The difference between the two methods is about eight percent, which is acceptable in our experiments. (authors)

[en] Objective: To study the clinical significance of changes of plasma Hcy and hepatic fibrosis markers levels in patients with NAFLD. Methods: Plasma Hcy (with biochemistry) and serum HA, PCIII, CIV, LN(with RIA) levels were determined in 133 patients with uncomplicated NAFLD, 124 patients with non-alcoholic steatohepatitis (NASH i.e.NAFLD complicated with ALT>2 x normal upper range over 4 weeks) and 100 controls. Results: In patients with uncomplicated NAFLD, the Hcy, HA, PCIII levels were significantly higher than those in controls (P<0.05), but the CIV and LN levels were only insignificantly raised (P>0.05). In patients with NASH, the levels of Hcy and other 4 markers were all significantly higher than those in the controls (P<0.05 or P<0.01). The altogether 257 patients with NAFLD could be divided into: mild (n=138), moderate (n=74) and advanced (n=45) degrees according to the CT value. Plasma Hcy and other 4 markers levels in patients with advanced degree NAFLD were significantly higher than those in patients with NAFLD of moderate and mild degrees (P<0.01), but the levels in patients with mild degree of NAFLD were not significantly different from the levels in patients with moderate degree of NAFLD (P>0.05). Conclusion: Plasma Hcy, HA, PCIII, CIV and LN levels were raised in patients with NAFLD, especially in patients with advanced degree of NAFLD and NASH. (authors)

[en] A wire scanner is used in the beam halo experiment at the Institute of High Energy Physics (IHEP) to measure the beam halo for the study of beam halo dynamics. The beam energy in the FODO transport line is 3.5 MeV and the peak current is 24 mA. Firstly we get the emittance value for the vertical and the horizontal plane respectively by measuring the matched beam. Then we measure the beam halo of the mismatched beam. (author)