[en] Since the majority of ischaemic cerebral infarcts is caused by thromboemboli, we determined the benefit of firbrinolytic therapy in acute stroke. Thromboemboli were induced in the middle cerebral artery of 21 dogs. Urokinase was started at different time intervals after infarction (1, 3 and 5 hours) at a rate of 1000 IU/kg/min. Angiographically controlled thrombolysis was achieved in all 15 treated cases, whereas in the control group (n=6) no case of recanalisation was observed. Systemic fibrinolysis occurred in all cases. Postmortem examinations of the brains showed no intracerebral haemorrhages. Our findings indicate the urokinase treatment may be of value in acute ischaemic stroke. (orig.)

[en] This paper deals with a numerical investigation of the film cooling effectiveness on five different curved surfaces and a flat surface. The models consist of 11 rectangular cross-sectioned injection holes aligned in a single row. The blowing ratios are from 0.5 to 2.0, and the injection angle with respect to the horizontal plane is 30^o. The hole geometry, the slope of the curved surface and the blowing ratio have important effects on the film cooling effectiveness. The results show that the film cooling effectiveness of a given curved surface, both along the mainstream and the spanwise direction, depends on the optimum selection of the parameters mentioned above