[en] A successive anchoring of Ti(NMe_2)_4, cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1′-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on silica was conducted by SOMC strategy in moderate conditions. The silica, monitored by in-situ Fourier transform infrared spectroscopy (in-situ FT-IR), was pretreated at different temperatures (200, 500 and 800 °C). The ligand tailored silica-supported titanium complexes were characterized by in-situ FT-IR, "1"3C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), X-ray absorption near edge structure (XANES) and elemental analysis in detail, verifying that the surface titanium species are single sited. The catalytic activity of the ligand tailored single-site silica supported titanium complexes was evaluated by a cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the dehydroxylation temperatures of silica and the configuration of the ligands. - Graphical abstract: The ligand-tailored silica supported “single site” titanium complexes were synthesized by SOMC strategy and fully characterized. Their catalytic activity were evaluated by benzaldehyde silylcyanation. - Highlights: • Single-site silica supported Ti active species was prepared by SOMC technique. • O-donor ligand tailored Ti surface species was synthesized. • The surface species was characterized by XPS, "1"3C CP-MAS NMR, XANES etc. • Catalytic activity of the Ti active species in silylcyanation reaction was evaluated

[en] Based on the SinoMOS 1 μm 40 V CMOS process, a novel power factor contention (PFC) converter with a low-power variable frequency function is presented. The circuit introduces a multi-vector error amplifier and a programmable oscillator to achieve frequency modulation, which provides a rapid dynamic response and precise output voltage clamping with low power in the entire load. According to the external load variation, the system can modulate the circuit operating frequency linearly, thereby ensuring that the PFC converter can work in frequency conversion-mode. Measured results show that the normal operating frequency of the PFC converter is 5-6 kHz, the start-up current is 36 μA, the stable operating current is only 2.43 mA, the efficiency is 97.3%, the power factor (PF) is 0.988, THD is 3.8%, the load adjust rate is 3%, and the linear adjust rate is less than 1%. Both theoretical and practical results reveal that the power consumption of the whole supply system is reduced efficiently, especially when the load varies. The active die area of the PFC converter chip is 1.61 x 1.52 mm². (semiconductor integrated circuits)

[en] For low-power low total harmonic distortion (THD), based on the CSMC 0.5 μm BCD process, a novel boost power factor correction (PFC) converter in critical conduction mode is discussed and analyzed. Feedforward compensation design is introduced in order to increase the PWM duty cycle and supply more conversion energy near the input voltage zero-crossing points, thus regulating the inductor current of the PFC converter and compensating the system loop gain change with ac line voltage. Both theoretical and practical results reveal that the proposed PFC converter with feedforward compensation cell has better power factor and THD performance, and is suitable for low-power low THD design applications. The experimental THD of the boost PFC converter is 4.5%, the start-up current is 54 μA, the stable operating current is 3.85 mA, the power factor is 0.998 and the efficiency is 95.2%. (semiconductor integrated circuits)

[en] To meet the accuracy requirement for the bandgap voltage reference by the increasing data conversion precision of integrated circuits, a high-order curvature-compensated bandgap voltage reference is presented employing the characteristic of bipolar transistor current gain exponentially changing with temperature variations. In addition, an over-temperature protection circuit with a thermal hysteresis function to prevent thermal oscillation is proposed. Based on the CSMC 0.5 μm 20 V BCD process, the designed circuit is implemented; the active die area is 0.17 x 0.20 mm². Simulation and testing results show that the temperature coefficient is 13.7ppm/K with temperature ranging from -40 to 150 ⁰C, the power supply rejection ratio is -98.2 dB, the line regulation is 0.3 mV/V, and the power consumption is only 0.38 mW. The proposed bandgap voltage reference has good characteristics such as small area, low power consumption, good temperature stability, high power supply rejection ratio, as well as low line regulation. This circuit can effectively prevent thermal oscillation and is suitable for on-chip voltage reference in high precision analog, digital and mixed systems. (semiconductor integrated circuits)

[en] Multidrug resistance (MDR) is a major obstacle to the treatment of gastric cancer (GC). Using a phage display approach, we previously obtained the peptide GMBP1, which specifically binds to the surface of MDR gastric cancer cells and is subsequently internalized. Furthermore, GMBP1 was shown to have the potential to reverse the MDR phenotype of gastric cancer cells, and GRP78 was identified as the receptor for this peptide. The present study aimed to investigate the mechanism of peptide GMBP1 and its receptor GRP78 in modulating gastric cancer MDR. Fluorescence-activated cell sorting (FACS) and immunofluorescence staining were used to investigate the subcellular location and mechanism of GMBP1 internalization. iTRAQ was used to identify the MDR-associated downstream targets of GMBP1. Differentially expressed proteins were identified in GMBP1-treated compared to untreated SGC7901/ADR and SGC7901/VCR cells. GO and KEGG pathway analyses of the differentially expressed proteins revealed the interconnection of these proteins, the majority of which are involved in MDR. Two differentially expressed proteins were selected and validated by western blotting. GMBP1 and its receptor GRP78 were found to be localized in the cytoplasm of GC cells, and GRP78 can mediate the internalization of GMBP1 into MDR cells through the transferrin-related pathway. In total, 3,752 and 3,749 proteins were affected in GMBP1-treated SGC7901/ADR and SGC7901/VCR cells, respectively, involving 38 and 79 KEGG pathways. Two differentially expressed proteins, CTBP2 and EIF4E, were selected and validated by western blotting. This study explored the role and downstream mechanism of GMBP1 in GC MDR, providing insight into the role of endoplasmic reticulum stress protein GRP78 in the MDR of cancer cells. The online version of this article (doi:10.1186/s12885-015-1361-3) contains supplementary material, which is available to authorized users

[en] A novel hydrothermal process using p-nitrobenzoic acid as structure-directing agent has been employed to synthesize plate-shaped WO₃ nanostructures containing holes. The p-nitrobenzoic acid plays a critical role in the synthesis of such novel WO₃ nanoplates. The morphology, structure and optical property of the WO₃ nanoplates have been characterized by transmission electron microcopy (TEM), scanning electron microcopy (SEM), X-ray diffraction (XRD) and photoluminescence (PL). The lateral size of the nanoplates is 500-1000 nm, and the thickness is about 80 nm. The formation mechanism of WO₃ nanoplates is discussed briefly. The gas sensitivity of WO₃ nanoplates was studied to ethanol and acetone at different operation temperatures and concentrations. Furthermore, the WO₃ nanoplate-based gas sensor exhibits high sensitivity for ethanol and acetone as well as quick response and recovery time at low temperature.

[en] Constructing bimetallic phosphides is an effective strategy to develop high-performance non-noble metal based electrochemical water splitting. Here, this article reports that bimetal-organic framework materials were directly grown on Ni foam by an electrodeposition assisted hydrothermal method as precursors, and the corresponding phosphides were obtained by phosphating as efficient bifunctional catalysts for an oxygen evolution reaction (OER) and a hydrogen evolution reaction (HER) in an alkaline medium. The experiments show that the phosphide obtained by phosphating ZIF-67 doped with iron shows better electrocatalytic activity. CoFeP/NF can produce a current density of 50 mA cm^-2 with an overpotential of 204 mV when catalyzing the OER reaction. When catalyzing the HER reaction, only a lower overpotential of 350 mV is required to produce a high current density of 50 mA cm^-2. In the two-electrode system catalytic water decomposition experiment, a high current density of 50 mA cm^-2 can be produced at a potential of 1.81 V. (authors)