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[en] Quaternary ammonium groups were introduced to Starburst polyamidoamine (PAMAM) dendrimers for a gene carrier. These quaternary dendritic carriers exhibited reduced cytotoxicity on 293T cells compared to parent dendrimers examined and their transfection efficiency were similar with parent dendrimers. Quaternization could be a promising tool to improve properties of dendrimers as a gene delivery carrier
Journal
Bulletin of the Korean Chemical Society; ISSN 0253-2964; 
; v. 24(11); p. 1637-1640
; v. 24(11); p. 1637-1640